GenTIGSA Gene Database on Rare Genetic Disorders
  Beta Version

Lists of Rare Genetic Disorders  

Restrictive Cardiomyopathy(Cardiomyopathies, Restrictive) 
An Autosomal dominant, Autosomal recessive mode(s) within the Cardiovascular disorders category
Reported Pathogenic variants
Candidate Gene Information
S.No. Name/GeneID Description Cytogentic Band Gene Location on genomic DNA Gene Length Exons Details Gene Cross-References
1 TNNT2/7139 troponin T2, cardiac type 1q32.1 Chr1, NC_000001.11
(201359014..201377680, complement)
18667 nt 17 More... OMIM gene
gnomAD browser
EnsEMBL
GeneCards
ClinGen gene

2 MYH7/4625 myosin heavy chain 7 14q11.2 Chr14, NC_000014.9
(23412740..23435660, complement)
22921 nt 40 More... OMIM gene
gnomAD browser
EnsEMBL
GeneCards
ClinGen gene

3 TNNI3/7137 troponin I3, cardiac type 19q13.42 Chr19, NC_000019.10
(55151767..55157732, complement)
5966 nt 8 More... OMIM gene
gnomAD browser
EnsEMBL
GeneCards
ClinGen gene

4 MYPN/84665 myopalladin 10q21.3 Chr10, NC_000010.11
(68087897..68212017)
124121 nt 28 More... OMIM gene
gnomAD browser
EnsEMBL
GeneCards
ClinGen gene

5 FLNC/2318 filamin C 7q32.1 Chr7, NC_000007.14
(128830406..128859272)
28867 nt 48 More... OMIM gene
gnomAD browser
EnsEMBL
GeneCards
ClinGen gene

6 PDLIM3/27295 PDZ and LIM domain 3 4q35.1 Chr4, NC_000004.12
(185500660..185535507, complement)
34848 nt 9 More... OMIM gene
gnomAD browser
EnsEMBL
GeneCards
ClinGen gene

7 TTN/7273 titin 2q31.2 Chr2, NC_000002.12
(178525989..178807423, complement)
281435 nt 364 More... OMIM gene
gnomAD browser
EnsEMBL
GeneCards
ClinGen gene

Variant Information             Highlighted rows indicate variants are reported from India
Disorder Cross-References:      Orphanet                    GTR          MedGen          MalaCards          EMBL-EBI OLS    Monarch Initiative          Human Phenotype Ontology          NORD     

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