Multiple Myeloma(Kahler disease) Explore Disorder's Alias
An Somatic mutation mode(s) within the Cancer disorders category
Candidate Gene Information
An Somatic mutation mode(s) within the Cancer disorders category
Reported Pathogenic variants
| S.No. | Name/GeneID | Description | Cytogentic Band | Gene Location on genomic DNA | Gene Length | Exons | Details | Gene Cross-References |
| 1 | FGFR3/2261 | fibroblast growth factor receptor 3 | 4p16.3 | Chr4, NC_000004.12 (1793293..1808867) |
15575 nt | 19 | More... | OMIM gene gnomAD browser EnsEMBL GeneCards ClinGen gene |
| 2 | BRAF/673 | B-Raf proto-oncogene, serine/threonine kinase | 7q34 | Chr7, NC_000007.14 (140713328..140924929, complement) |
211602 nt | 24 | More... | OMIM gene gnomAD browser EnsEMBL GeneCards ClinGen gene |
| 3 | TP53/7157 | tumor protein p53 | 17p13.1 | Chr17, NC_000017.11 (7668421..7687490, complement) |
19070 nt | 11 | More... | OMIM gene gnomAD browser EnsEMBL GeneCards ClinGen gene |
| 4 | TRAF5/7188 | TNF receptor associated factor 5 | 1q32.3 | Chr1, NC_000001.11 (211326635..211374946) |
48312 nt | 13 | More... | OMIM gene gnomAD browser EnsEMBL GeneCards ClinGen gene |
| 5 | CDKN2C/1031 | cyclin dependent kinase inhibitor 2C | 1p32.3 | Chr1, NC_000001.11 (50968706..50974634) |
5929 nt | 3 | More... | OMIM gene gnomAD browser EnsEMBL GeneCards ClinGen gene |
| 6 | BARD1/580 | BRCA1 associated RING domain 1 | 2q35 | Chr2, NC_000002.12 (214725646..214809683, complement) |
84038 nt | 13 | More... | OMIM gene gnomAD browser EnsEMBL GeneCards ClinGen gene |
| 7 | HDAC4/9759 | histone deacetylase 4 | 2q37.3 | Chr2, NC_000002.12 (239048168..239401649, complement) |
353482 nt | 34 | More... | OMIM gene gnomAD browser EnsEMBL GeneCards ClinGen gene |
| 8 | DNMT3A/1788 | DNA methyltransferase 3 alpha | 2p23.3 | Chr2, NC_000002.12 (25227874..25342590, complement) |
114717 nt | 35 | More... | OMIM gene gnomAD browser EnsEMBL GeneCards ClinGen gene |
| 9 | TET3/200424 | tet methylcytosine dioxygenase 3 | 2p13.1 | Chr2, NC_000002.12 (73983631..74135498) |
151868 nt | 17 | More... | OMIM gene gnomAD browser EnsEMBL GeneCards ClinGen gene |
| 10 | CRBN/51185 | cereblon | 3p26.2 | Chr3, NC_000003.12 (3149633..3179717, complement) |
30085 nt | 12 | More... | OMIM gene gnomAD browser EnsEMBL GeneCards ClinGen gene |
| 11 | MST1R/4486 | macrophage stimulating 1 receptor | 3p21.31 | Chr3, NC_000003.12 (49887002..49903873, complement) |
16872 nt | 21 | More... | OMIM gene gnomAD browser EnsEMBL GeneCards ClinGen gene |
| 12 | BAP1/8314 | BRCA1 associated protein 1 | 3p21.1 | Chr3, NC_000003.12 (52401008..52410008, complement) |
9001 nt | 17 | More... | OMIM gene gnomAD browser EnsEMBL GeneCards ClinGen gene |
| 13 | TET2/54790 | tet methylcytosine dioxygenase 2 | 4q24 | Chr4, NC_000004.12 (105145875..105279803) |
133929 nt | 14 | More... | OMIM gene gnomAD browser EnsEMBL GeneCards ClinGen gene |
| 14 | FAT1/2195 | FAT atypical cadherin 1 | 4q35.2 | Chr4, NC_000004.12 (186587794..186726696, complement) |
138903 nt | 29 | More... | OMIM gene gnomAD browser EnsEMBL GeneCards ClinGen gene |
| 15 | IL7R/3575 | interleukin 7 receptor | 5p13.2 | Chr5, NC_000005.10 (35856891..35879603) |
22713 nt | 8 | More... | OMIM gene gnomAD browser EnsEMBL GeneCards ClinGen gene |
| 16 | SGK1/6446 | serum/glucocorticoid regulated kinase 1 | 6q23.2 | Chr6, NC_000006.12 (134169256..134318112, complement) |
148857 nt | 17 | More... | OMIM gene gnomAD browser EnsEMBL GeneCards ClinGen gene |
| 17 | LATS1/9113 | large tumor suppressor kinase 1 | 6q25.1 | Chr6, NC_000006.12 (149658153..149718101, complement) |
59949 nt | 18 | More... | OMIM gene gnomAD browser EnsEMBL GeneCards ClinGen gene |
| 18 | H3C1/8350 | H3 clustered histone 1 | 6p22.2 | Chr6, NC_000006.12 (26020451..26020958) |
508 nt | 1 | More... | OMIM gene gnomAD browser EnsEMBL GeneCards ClinGen gene |
| 19 | H1-4/3008 | H1.4 linker histone, cluster member | 6p22.2 | Chr6, NC_000006.12 (26156329..26157115) |
787 nt | 1 | More... | OMIM gene gnomAD browser EnsEMBL GeneCards ClinGen gene |
| 20 | H2AC16/8332 | H2A clustered histone 16 | 6p22.1 | Chr6, NC_000006.12 (27865317..27865798) |
482 nt | 1 | More... | OMIM gene gnomAD browser EnsEMBL GeneCards ClinGen gene |
| 21 | H2AC17/8336 | H2A clustered histone 17 | 6p22.1 | Chr6, NC_000006.12 (27892699..27893185, complement) |
487 nt | 1 | More... | OMIM gene gnomAD browser EnsEMBL GeneCards ClinGen gene |
| 22 | KMT2C/58508 | lysine methyltransferase 2C | 7q36.1 | Chr7, NC_000007.14 (152134925..152436003, complement) |
301079 nt | 59 | More... | OMIM gene gnomAD browser EnsEMBL GeneCards ClinGen gene |
| 23 | RXRA/6256 | retinoid X receptor alpha | 9q34.2 | Chr9, NC_000009.12 (134326455..134440585) |
114131 nt | 12 | More... | OMIM gene gnomAD browser EnsEMBL GeneCards ClinGen gene |
| 24 | YAP1/10413 | Yes1 associated transcriptional regulator | 11q22.1 | Chr11, NC_000011.10 (102110447..102233424) |
122978 nt | 11 | More... | OMIM gene gnomAD browser EnsEMBL GeneCards ClinGen gene |
| 25 | ATM/472 | ATM serine/threonine kinase | 11q22.3 | Chr11, NC_000011.10 (108223067..108369102) |
146036 nt | 67 | More... | OMIM gene gnomAD browser EnsEMBL GeneCards ClinGen gene |
| 26 | SH2B3/10019 | SH2B adaptor protein 3 | 12q24.12 | Chr12, NC_000012.12 (111404730..111451623) |
46894 nt | 13 | More... | OMIM gene gnomAD browser EnsEMBL GeneCards ClinGen gene |
| 27 | NCOR2/9612 | nuclear receptor corepressor 2 | 12q24.31 | Chr12, NC_000012.12 (124324415..124567612, complement) |
243198 nt | 49 | More... | OMIM gene gnomAD browser EnsEMBL GeneCards ClinGen gene |
| 28 | FLT3/2322 | fms related receptor tyrosine kinase 3 | 13q12.2 | Chr13, NC_000013.11 (28003274..28100576, complement) |
97303 nt | 27 | More... | OMIM gene gnomAD browser EnsEMBL GeneCards ClinGen gene |
| 29 | DIS3/22894 | DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease | 13q21.33 | Chr13, NC_000013.11 (72752169..72781900, complement) |
29732 nt | 22 | More... | OMIM gene gnomAD browser EnsEMBL GeneCards ClinGen gene |
| 30 | NKX2-1/7080 | NK2 homeobox 1 | 14q13.3 | Chr14, NC_000014.9 (36516397..36520232, complement) |
3836 nt | 3 | More... | OMIM gene gnomAD browser EnsEMBL GeneCards ClinGen gene |
| 31 | ARID4A/5926 | AT-rich interaction domain 4A | 14q23.1 | Chr14, NC_000014.9 (58298555..58373876) |
75322 nt | 28 | More... | OMIM gene gnomAD browser EnsEMBL GeneCards ClinGen gene |
| 32 | MGA/23269 | MAX dimerization protein MGA | 15q15.1 | Chr15, NC_000015.10 (41621224..41769940) |
148717 nt | 28 | More... | OMIM gene gnomAD browser EnsEMBL GeneCards ClinGen gene |
| 33 | CREBBP/1387 | CREB binding protein | 16p13.3 | Chr16, NC_000016.10 (3725054..3880713, complement) |
155660 nt | 33 | More... | OMIM gene gnomAD browser EnsEMBL GeneCards ClinGen gene |
| 34 | CYLD/1540 | CYLD lysine 63 deubiquitinase | 16q12.1 | Chr16, NC_000016.10 (50742086..50801935) |
59850 nt | 23 | More... | OMIM gene gnomAD browser EnsEMBL GeneCards ClinGen gene |
| 35 | NF1/4763 | neurofibromin 1 | 17q11.2 | Chr17, NC_000017.11 (31094927..31377677) |
282751 nt | 58 | More... | OMIM gene gnomAD browser EnsEMBL GeneCards ClinGen gene |
| 36 | TCF3/6929 | transcription factor 3 | 19p13.3 | Chr19, NC_000019.10 (1609292..1652615, complement) |
43324 nt | 21 | More... | OMIM gene gnomAD browser EnsEMBL GeneCards ClinGen gene |
| 37 | PIK3R2/5296 | phosphoinositide-3-kinase regulatory subunit 2 | 19p13.11 | Chr19, NC_000019.10 (18153163..18170532) |
17370 nt | 16 | More... | OMIM gene gnomAD browser EnsEMBL GeneCards ClinGen gene |
| 38 | ERF/2077 | ETS2 repressor factor | 19q13.2 | Chr19, NC_000019.10 (42247569..42255128, complement) |
7560 nt | 8 | More... | OMIM gene gnomAD browser EnsEMBL GeneCards ClinGen gene |
| 39 | SAMHD1/25939 | SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 | 20q11.23 | Chr20, NC_000020.11 (36889773..36951708, complement) |
61936 nt | 16 | More... | OMIM gene gnomAD browser EnsEMBL GeneCards ClinGen gene |
| 40 | AURKA/6790 | aurora kinase A | 20q13.2 | Chr20, NC_000020.11 (56369390..56392215, complement) |
22826 nt | 11 | More... | OMIM gene gnomAD browser EnsEMBL GeneCards ClinGen gene |
| 41 | BCORL1/63035 | BCL6 corepressor like 1 | Xq26.1 | ChrX, NC_000023.11 (129980313..130058071) |
77759 nt | 21 | More... | OMIM gene gnomAD browser EnsEMBL GeneCards ClinGen gene |
| 42 | EIF1AX/1964 | eukaryotic translation initiation factor 1A X-linked | Xp22.12 | ChrX, NC_000023.11 (20124525..20141838, complement) |
17314 nt | 7 | More... | OMIM gene gnomAD browser EnsEMBL GeneCards ClinGen gene |
| 43 | KDM5C/8242 | lysine demethylase 5C | Xp11.22 | ChrX, NC_000023.11 (53176277..53225207, complement) |
48931 nt | 29 | More... | OMIM gene gnomAD browser EnsEMBL GeneCards ClinGen gene |
| 44 | P2RY8/286530 | P2Y receptor family member 8 | Xp22.33;Yp11.2 | ChrX, NC_000023.11 (1462581..1537185, complement) |
74605 nt | 8 | More... | OMIM gene gnomAD browser EnsEMBL GeneCards ClinGen gene |
| Variant Information | ||||||||
| Disorder Cross-References: GARD GTR MalaCards NORD | ||||||||
Patient care services
Clinical Symptoms & Disabilities
Prevalence
| Under development |