Dilated Cardiomyopathy 1A(LMNA familial isolated dilated cardiomyopathy) Explore Disorder's Alias
An Autosomal dominant mode(s) within the Cardiovascular disorders category
Candidate Gene Information
An Autosomal dominant mode(s) within the Cardiovascular disorders category
Reported Pathogenic variants
| S.No. | Name/GeneID | Description | Cytogentic Band | Gene Location on genomic DNA | Gene Length | Exons | Details | Gene Cross-References |
| 1 | LMNA/4000 | lamin A/C | 1q22 | Chr1, NC_000001.11 (156082573..156140081) |
57509 nt | 17 | More... | OMIM gene gnomAD browser EnsEMBL GeneCards ClinGen gene |
| 2 | ACTN2/88 | actinin alpha 2 | 1q43 | Chr1, NC_000001.11 (236686499..236764631) |
78133 nt | 23 | More... | OMIM gene gnomAD browser EnsEMBL GeneCards ClinGen gene |
| 3 | HAND2/9464 | heart and neural crest derivatives expressed 2 | 4q34.1 | Chr4, NC_000004.12 (173526091..173530229, complement) |
4139 nt | 2 | More... | OMIM gene gnomAD browser EnsEMBL GeneCards ClinGen gene |
| 4 | TTN/7273 | titin | 2q31.2 | Chr2, NC_000002.12 (178525989..178807423, complement) |
281435 nt | 364 | More... | OMIM gene gnomAD browser EnsEMBL GeneCards ClinGen gene |
| 5 | DMD/1756 | dystrophin | Xp21.1 | ChrX, NC_000023.11 (31119222..33339388, complement) |
2220167 nt | 89 | More... | OMIM gene gnomAD browser EnsEMBL GeneCards ClinGen gene |
| 6 | SEMA3E/9723 | semaphorin 3E | 7q21.11 | Chr7, NC_000007.14 (83363238..83649139, complement) |
285902 nt | 18 | More... | OMIM gene gnomAD browser EnsEMBL GeneCards ClinGen gene |
| 7 | SYNE1/23345 | spectrin repeat containing nuclear envelope protein 1 | 6q25.2 | Chr6, NC_000006.12 (152121687..152637362, complement) |
515676 nt | 153 | More... | OMIM gene gnomAD browser EnsEMBL GeneCards ClinGen gene |
| 8 | NFATC2/4773 | nuclear factor of activated T cells 2 | 20q13.2 | Chr20, NC_000020.11 (51386963..51562839, complement) |
175877 nt | 13 | More... | OMIM gene gnomAD browser EnsEMBL GeneCards ClinGen gene |
| 9 | RAPGEF5/9771 | Rap guanine nucleotide exchange factor 5 | 7p15.3 | Chr7, NC_000007.14 (22118236..22357154, complement) |
238919 nt | 31 | More... | OMIM gene gnomAD browser EnsEMBL GeneCards ClinGen gene |
| 10 | FLNC/2318 | filamin C | 7q32.1 | Chr7, NC_000007.14 (128830406..128859272) |
28867 nt | 48 | More... | OMIM gene gnomAD browser EnsEMBL GeneCards ClinGen gene |
| 11 | UNC45B/146862 | unc-45 myosin chaperone B | 17q12 | Chr17, NC_000017.11 (35147817..35189345) |
41529 nt | 20 | More... | OMIM gene gnomAD browser EnsEMBL GeneCards ClinGen gene |
| Variant Information Highlighted rows indicate variants are reported from India | ||||||||
| Disorder Cross-References: Orphanet OMIM GARD GTR MedGen MalaCards EMBL-EBI OLS Monarch Initiative NORD | ||||||||