GenTIGSA Gene Database on Rare Genetic Disorders

Lists of Rare Genetic Disorders  

Shwachman-Diamond Syndrome 1(Lipomatosis of pancreas, congenital)      Explore Disorder's Alias
An Autosomal recessive mode(s) within the Multisystemic disorders category
Reported Pathogenic variants
Candidate Gene Information
S.No. Name/GeneID Description Cytogentic Band Gene Location on genomic DNA Gene Length Exons Details Gene Cross-References
1 SBDS/51119 SBDS ribosome maturation factor 7q11.21 Chr7, NC_000007.14
(66987680..66995586, complement)
7907 nt 5 More... OMIM gene
gnomAD browser
EnsEMBL
GeneCards
ClinGen gene

2 SRP54/6729 signal recognition particle 54 14q13.2 Chr14, NC_000014.9
(34982992..35029567)
46576 nt 17 More... OMIM gene
gnomAD browser
EnsEMBL
GeneCards
ClinGen gene

3 SRP19/6728 signal recognition particle 19 5q22.2 Chr5, NC_000005.10
(112861287..112898371)
37085 nt 6 More... OMIM gene
gnomAD browser
EnsEMBL
GeneCards
ClinGen gene

4 SRPRA/6734 SRP receptor subunit alpha 11q24.2 Chr11, NC_000011.10
(126235930..126268895, complement)
32966 nt 16 More... OMIM gene
gnomAD browser
EnsEMBL
GeneCards
ClinGen gene

Variant Information             Highlighted rows indicate variants are reported from India
Disorder Cross-References:      OMIM          GARD          GTR          MedGen          MalaCards          EMBL-EBI OLS    Monarch Initiative          NORD     

Patient care services
Clinical Symptoms & Disabilities