Non-small Cell Lung Carcinoma(Non-small cell lung cancer)
An Unknown mode(s) within the Cancer disorders category
Candidate Gene Information
An Unknown mode(s) within the Cancer disorders category
Reported Pathogenic variants
| S.No. | Name/GeneID | Description | Cytogentic Band | Gene Location on genomic DNA | Gene Length | Exons | Details | Gene Cross-References |
| 1 | BRAF/673 | B-Raf proto-oncogene, serine/threonine kinase | 7q34 | Chr7, NC_000007.14 (140713328..140924929, complement) |
211602 nt | 24 | More... | OMIM gene gnomAD browser EnsEMBL GeneCards ClinGen gene |
| 2 | IRF1/3659 | interferon regulatory factor 1 | 5q31.1 | Chr5, NC_000005.10 (132481609..132490773, complement) |
9165 nt | 10 | More... | OMIM gene gnomAD browser EnsEMBL GeneCards ClinGen gene |
| 3 | ERBB2/2064 | erb-b2 receptor tyrosine kinase 2 | 17q12 | Chr17, NC_000017.11 (39688094..39728658) |
40565 nt | 35 | More... | OMIM gene gnomAD browser EnsEMBL GeneCards ClinGen gene |
| 4 | KRAS/3845 | KRAS proto-oncogene, GTPase | 12p12.1 | Chr12, NC_000012.12 (25205246..25250929, complement) |
45684 nt | 7 | More... | OMIM gene gnomAD browser EnsEMBL GeneCards ClinGen gene |
| 5 | EGFR/1956 | epidermal growth factor receptor | 7p11.2 | Chr7, NC_000007.14 (55019017..55211628) |
192612 nt | 32 | More... | OMIM gene gnomAD browser EnsEMBL GeneCards ClinGen gene |
| 6 | PIK3CA/5290 | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | 3q26.32 | Chr3, NC_000003.12 (179148126..179240093) |
91968 nt | 22 | More... | OMIM gene gnomAD browser EnsEMBL GeneCards ClinGen gene |
| 7 | NRAS/4893 | NRAS proto-oncogene, GTPase | 1p13.2 | Chr1, NC_000001.11 (114704469..114716771, complement) |
12303 nt | 7 | More... | OMIM gene gnomAD browser EnsEMBL GeneCards ClinGen gene |
| 8 | DDR2/4921 | discoidin domain receptor tyrosine kinase 2 | 1q23.3 | Chr1, NC_000001.11 (162630863..162787405) |
156543 nt | 22 | More... | OMIM gene gnomAD browser EnsEMBL GeneCards ClinGen gene |
| 9 | MAP2K1/5604 | mitogen-activated protein kinase kinase 1 | 15q22.31 | Chr15, NC_000015.10 (66386912..66491544) |
104633 nt | 12 | More... | OMIM gene gnomAD browser EnsEMBL GeneCards ClinGen gene |
| 10 | ALK/238 | ALK receptor tyrosine kinase | 2p23.2 | Chr2, NC_000002.12 (29192774..29921586, complement) |
728813 nt | 29 | More... | OMIM gene gnomAD browser EnsEMBL GeneCards ClinGen gene |
| 11 | ARAF/369 | A-Raf proto-oncogene, serine/threonine kinase | Xp11.3 | ChrX, NC_000023.11 (47561205..47571908) |
10704 nt | 16 | More... | OMIM gene gnomAD browser EnsEMBL GeneCards ClinGen gene |
| 12 | STK11/6794 | serine/threonine kinase 11 | 19p13.3 | Chr19, NC_000019.10 (1205778..1228431) |
22654 nt | 12 | More... | OMIM gene gnomAD browser EnsEMBL GeneCards ClinGen gene |
| 13 | NOTCH1/4851 | notch receptor 1 | 9q34.3 | Chr9, NC_000009.12 (136494433..136546048, complement) |
51616 nt | 34 | More... | OMIM gene gnomAD browser EnsEMBL GeneCards ClinGen gene |
| Variant Information | ||||||||
| Disorder Cross-References: GTR MedGen MalaCards EMBL-EBI OLS Monarch Initiative Human Phenotype Ontology NORD | ||||||||
Patient care services
Clinical Symptoms & Disabilities
Prevalence
| Under development |