Gastrointestinal Stroma Tumor(Gastrointestinal stromal sarcoma) Explore Disorder's Alias
An Autosomal dominant mode(s) within the Cancer disorders category
Candidate Gene Information
An Autosomal dominant mode(s) within the Cancer disorders category
Reported Pathogenic variants
| S.No. | Name/GeneID | Description | Cytogentic Band | Gene Location on genomic DNA | Gene Length | Exons | Details | Gene Cross-References |
| 1 | PDGFRA/5156 | platelet derived growth factor receptor alpha | 4q12 | Chr4, NC_000004.12 (54229293..54298245) |
68953 nt | 30 | More... | OMIM gene gnomAD browser EnsEMBL GeneCards ClinGen gene |
| 2 | KIT/3815 | KIT proto-oncogene, receptor tyrosine kinase | 4q12 | Chr4, NC_000004.12 (54657957..54740715) |
82759 nt | 21 | More... | OMIM gene gnomAD browser EnsEMBL GeneCards ClinGen gene |
| 3 | SDHB/6390 | succinate dehydrogenase complex iron sulfur subunit B | 1p36.13 | Chr1, NC_000001.11 (17018722..17054032, complement) |
35311 nt | 8 | More... | OMIM gene gnomAD browser EnsEMBL GeneCards ClinGen gene |
| 4 | SDHC/6391 | succinate dehydrogenase complex subunit C | 1q23.3 | Chr1, NC_000001.11 (161314381..161363206) |
48826 nt | 9 | More... | OMIM gene gnomAD browser EnsEMBL GeneCards ClinGen gene |
| 5 | SDHA/6389 | succinate dehydrogenase complex flavoprotein subunit A | 5p15.33 | Chr5, NC_000005.10 (218320..268746) |
50427 nt | 17 | More... | OMIM gene gnomAD browser EnsEMBL GeneCards ClinGen gene |
| Variant Information | ||||||||
| Disorder Cross-References: GARD GTR MalaCards NORD | ||||||||
Patient care services
Clinical Symptoms & Disabilities
Prevalence
| Under development |