Acute Megakaryoblastic Leukemia(Acute megakaryocytic leukemia)
An Unknown mode(s) within the Cancer disorders category
Candidate Gene Information
An Unknown mode(s) within the Cancer disorders category
Reported Pathogenic variants
| S.No. | Name/GeneID | Description | Cytogentic Band | Gene Location on genomic DNA | Gene Length | Exons | Details | Gene Cross-References |
| 1 | GATA1/2623 | GATA binding protein 1 | Xp11.23 | ChrX, NC_000023.11 (48786590..48794311) |
7722 nt | 6 | More... | OMIM gene gnomAD browser EnsEMBL GeneCards ClinGen gene |
| 2 | TP53/7157 | tumor protein p53 | 17p13.1 | Chr17, NC_000017.11 (7668421..7687490, complement) |
19070 nt | 11 | More... | OMIM gene gnomAD browser EnsEMBL GeneCards ClinGen gene |
| 3 | JAK3/3718 | Janus kinase 3 | 19p13.11 | Chr19, NC_000019.10 (17824782..17847982, complement) |
23201 nt | 24 | More... | OMIM gene gnomAD browser EnsEMBL GeneCards ClinGen gene |
| 4 | JAK1/3716 | Janus kinase 1 | 1p31.3 | Chr1, NC_000001.11 (64833229..65067746, complement) |
234518 nt | 30 | More... | OMIM gene gnomAD browser EnsEMBL GeneCards ClinGen gene |
| 5 | SETD2/29072 | SET domain containing 2, histone lysine methyltransferase | 3p21.31 | Chr3, NC_000003.12 (47016436..47164840, complement) |
148405 nt | 25 | More... | OMIM gene gnomAD browser EnsEMBL GeneCards ClinGen gene |
| 6 | RAD21/5885 | RAD21 cohesin complex component | 8q24.11 | Chr8, NC_000008.11 (116845934..116874776, complement) |
28843 nt | 14 | More... | OMIM gene gnomAD browser EnsEMBL GeneCards ClinGen gene |
| 7 | CTCF/10664 | CCCTC-binding factor | 16q22.1 | Chr16, NC_000016.10 (67562526..67639185) |
76660 nt | 13 | More... | OMIM gene gnomAD browser EnsEMBL GeneCards ClinGen gene |
| 8 | SUZ12/23512 | SUZ12 polycomb repressive complex 2 subunit | 17q11.2 | Chr17, NC_000017.11 (31937007..32001038) |
64032 nt | 17 | More... | OMIM gene gnomAD browser EnsEMBL GeneCards ClinGen gene |
| 9 | SRSF2/6427 | serine and arginine rich splicing factor 2 | 17q25.1 | Chr17, NC_000017.11 (76734115..76737411, complement) |
3297 nt | 5 | More... | OMIM gene gnomAD browser EnsEMBL GeneCards ClinGen gene |
| Variant Information | ||||||||
| Disorder Cross-References: GTR MalaCards NORD | ||||||||
Patient care services
Clinical Symptoms & Disabilities
Prevalence
| Under development |