GenTIGSA Gene Database on Rare Genetic Disorders

Variants in ClinVar from 539 of 916 Rare Genetic Disorders of GenTIGS

Glycogen storage disease, type V

An  Autosomal recessive  mode(s) within the Metabolic disorders  category

Pathogenic 2
Pathogenic/Likely pathogenic 1
Uncertain significance 2

Variant name Variant type GRCH38 location Germline classification Molecular consequence dbSNP_ID Submitter
NM_002863.5(PYGL):c.2056G>C (p.Gly686Arg) Single nucleotide variant Chr14:50910016 Uncertain significance Missense variant rs2050377435 .Centre for Human Genetics
NM_002863.5(PYGL):c.72C>A (p.Asn24Lys) Single nucleotide variant Chr14:50944332 Pathogenic Missense variant rs1375868904 .Centre for Human Genetics
NM_002863.5(PYGL):c.1620+1G>C Single nucleotide variant Chr14:50913028 Pathogenic Splice donor variant rs113993981 .Centre for Human Genetics
.Kasturba Medical College, Manipal, Kasturba Medical College, Manipal, Manipal Academy of Higher Education, Manipal, India
.Neuberg Centre For Genomic Medicine, NCGM
.Suma Genomics
NM_002863.5(PYGL):c.2017G>A (p.Glu673Lys) Single nucleotide variant Chr14:50910055 Uncertain significance Missense variant rs113993984 .Centre for Human Genetics
NM_005609.4(PYGM):c.1768+1G>A Single nucleotide variant Chr11:64751923 Pathogenic/Likely pathogenic Splice donor variant rs771427957 .Kasturba Medical College, Manipal, Kasturba Medical College, Manipal, Manipal Academy of Higher Education, Manipal, India
.Lifecell International Pvt. Ltd

Indian Institutes & Variant Submission Overview
Chromosome-wise Variant Distribution