GenTIGSA Gene Database on Rare Genetic Disorders

Variants in ClinVar from 539 of 916 Rare Genetic Disorders of GenTIGS

Dyggve-Melchior-Clausen syndrome

An  Autosomal recessive  mode(s) within the Multisystemic disorders  category

Likely pathogenic 1
Pathogenic/Likely pathogenic 1

Variant name Variant type GRCH38 location Germline classification Molecular consequence dbSNP_ID Submitter
GRCh37/hg19 18q21.2(chr18:49286617-49331863)x1 Copy number loss Chr: Likely pathogenic .Department Of Genetics, Lifeline Super Speciality Hospital, Adoor.
NM_001353214.3(DYM):c.1728+2T>C Single nucleotide variant Chr18:49163683 Pathogenic/Likely pathogenic Splice donor variant rs2087482291 .Centre for Human Genetics
.Kasturba Medical College, Manipal, Kasturba Medical College, Manipal, Manipal Academy of Higher Education, Manipal, India

Indian Institutes & Variant Submission Overview
Chromosome-wise Variant Distribution