GenTIGSA Gene Database on Rare Genetic Disorders

Explore information by Inheritance Mode 

Autosomal recessive, X-linked recessive

Monogenic disorders list based on single and multiple genes


Disorder Name (Total=1) Aliases Category Gene Indian Reports Link
Severe combined immunodeficiency disease • Combined T and B cell inborn immunodeficiency
• Severe Combined Immune Deficiency
• Severe combined immunodeficiency
• severe combined immunodeficiency (disease)
Immune disorders ADA adenosine deaminase
IL7R interleukin 7 receptor
JAK3 Janus kinase 3
RAG1 recombination activating 1
RAG2 recombination activating 2
DCLRE1C DNA cross-link repair 1C
TTC7A tetratricopeptide repeat domain 7A
AK2 adenylate kinase 2
PGM3 phosphoglucomutase 3
MALT1 MALT1 paracaspase
PTPRC protein tyrosine phosphatase receptor type C
IKBKB inhibitor of nuclear factor kappa B kinase subunit beta
DOCK8 dedicator of cytokinesis 8
CD3G CD3 gamma subunit of T-cell receptor complex
MTHFD1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1
CORO1A coronin 1A
STK4 serine/threonine kinase 4
PNP purine nucleoside phosphorylase
LCK LCK proto-oncogene, Src family tyrosine kinase
FOXN1 forkhead box N1
CD3E CD3 epsilon subunit of T-cell receptor complex
CD3D CD3 delta subunit of T-cell receptor complex
Reports
Updated as of Sep 08, 2025
PubMed