GenTIGSA Gene Database on Rare Genetic Disorders

Select a RGD Category for details 

RGDs registry under the 'Liver disorders'
Disorder Name (Total=4) Aliases Sub-Category Gene Indian Reports Link
Alagille syndrome
Autosomal dominant
Biliary tract disorders JAG1 jagged canonical Notch ligand 1
NOTCH2 notch receptor 2
Reports
Updated as of Sep 15, 2022
PubMed
Primary biliary cholangitis
•Familial primary biliary cirrhosis
•Hanot syndrome
•Primary biliary cirrhosis
Biliary tract disorders TJP2 tight junction protein 2
Reports
Updated as of Jan 04, 2024
PubMed
Primary sclerosing cholangitis
•PSC
Biliary tract disorders Snhg10 small nucleolar RNA host gene 10
SEMA4D semaphorin 4D
GPR35 G protein-coupled receptor 35
STK4 serine/threonine kinase 4
Reports
Updated as of Jan 04, 2024
PubMed
Progressive familial intrahepatic cholestasis type 2
Autosomal recessive
•ABCB11 progressive familial intrahepatic cholestasis
•BSEP (bile salt export pump) deficiency
•BSEP deficiency
•cholestasis, progressive familial intrahepatic 2
•cholestasis, progressive familial intrahepatic, type 2
•PFIC2
•PFIC2 - progressive familial intrahepatic cholestasis type 2
•progressive familial intrahepatic cholestasis caused by mutation in abcb11
•Cholestasis, progressive familial intrahepatic 2
•PFIC2 Progressive familial intrahepatic cholestasis type 2
•Progressive familial intrahepatic cholestasis 2
Biliary tract disorders ABCB11 ATP binding cassette subfamily B member 11
Reports
Updated as of Jan 05, 2026
PubMed