Propionyl-CoA carboxylase subunit beta (PCCB) Associated conditions: 1. Propionic acidemia
| SNo. | Status | mRNA accession | Protein accession | Genomic DNA accession (Chromosome) | mRNA location on genomic DNA | Assembly | UniProtkb ID |
| 1 | REVIEWED | NM_000532.5 | NP_000523.2 | NC_000003.12 | (136250339..136330168) | Reference GRCh38.p14 Primary Assembly | - |
| 2 | REVIEWED | NM_001178014.2 | NP_001171485.1 | NC_000003.12 | (136250339..136330168) | Reference GRCh38.p14 Primary Assembly | - |
Transcript variants arise from alternative splicing during gene expression, producing multiple mRNA transcripts from a single gene, each encoding distinct protein isoforms.
Variant Information Propionyl-CoA carboxylase subunit beta (PCCB) Mutation Visualization Dashboard: Pathogenic variant distribution chart
ClinVar variants:Revealing mutagenic patterns
| SNo. | Reported in speceis | Evidence | Qualifier | GO term | Category | Pubmed Link |
| 1 | Homo sapiens | IEA | enables | nucleotide binding | Function | - |
| 2 | Homo sapiens | IBA | enables | propionyl-CoA carboxylase activity | Function | - |
| 3 | Homo sapiens | IDA | enables | propionyl-CoA carboxylase activity | Function | 6765947 |
| 4 | Homo sapiens | IEA | enables | propionyl-CoA carboxylase activity | Function | - |
| 5 | Homo sapiens | IPI | enables | protein binding | Function | 20725044 32296183 33961781 40205054 |
| 6 | Homo sapiens | IEA | enables | ATP binding | Function | - |
| 7 | Homo sapiens | HTP | located_in | mitochondrion | Component | 34800366 |
| 8 | Homo sapiens | IBA | is_active_in | mitochondrion | Component | - |
| 9 | Homo sapiens | TAS | located_in | mitochondrion | Component | 8188292 |
| 10 | Homo sapiens | IDA | located_in | mitochondrial matrix | Component | 16023992 |
| 11 | Homo sapiens | IEA | located_in | mitochondrial matrix | Component | - |
| 12 | Homo sapiens | NAS | located_in | mitochondrial matrix | Component | 29033250 |
| 13 | Homo sapiens | TAS | located_in | mitochondrial matrix | Component | - |
| 14 | Homo sapiens | TAS | located_in | cytosol | Component | - |
| 15 | Homo sapiens | NAS | involved_in | fatty acid metabolic process | Process | 29033250 |
| 16 | Homo sapiens | IEA | involved_in | fatty acid catabolic process | Process | - |
| 17 | Homo sapiens | NAS | involved_in | branched-chain amino acid metabolic process | Process | 29033250 |
| 18 | Homo sapiens | IEA | enables | ligase activity | Function | - |
| 19 | Homo sapiens | IC | involved_in | short-chain fatty acid catabolic process | Process | 6765947 |