Total 56 clinical symptoms reported for Wiskott-Aldrich syndrome
Abnormal platelet morphology |
An anomaly in platelet form, ultrastructure, or intracellular organelles.
Synonyms:Abnormal shape of platelets |
Very frequent |
Bruising susceptibility |
An ecchymosis (bruise) refers to the skin discoloration caused by the escape of blood into the tissues from ruptured blood vessels. This term refers to an abnormally increased susceptibility to bruising. The corresponding phenotypic abnormality is generally elicited on medical history as a report of frequent ecchymoses or bruising without adequate trauma.
Synonyms:Bruisability; Bruise easily; Bruising susceptibility; Easy bruisability; Easy bruising |
Very frequent |
Chronic diarrhea |
The presence of chronic diarrhea, which is usually taken to mean diarrhea that has persisted for over 4 weeks.
Synonyms:Chronic diarrhea |
Very frequent |
Chronic otitis media |
Chronic otitis media refers to fluid, swelling, or infection of the middle ear that does not heal and may cause permanent damage to the ear.
Synonyms:Chronic infections of the middle ear; Otitis media, chronic |
Very frequent |
Chronic pulmonary obstruction |
An anomaly that is characterized progressive airflow obstruction that is only partly reversible, inflammation in the airways, and systemic effects or comorbities.
Synonyms:Chronic obstructive pulmonary disease; COPD |
Very frequent |
Immunodeficiency |
Failure of the immune system to protect the body adequately from infection, due to the absence or insufficiency of some component process or substance.
Synonyms:Decreased immune function; Immune deficiency |
Very frequent |
Internal hemorrhage |
The presence of hemorrhage within the body.
Synonyms:Internal bleeding |
Very frequent |
Lymphopenia |
A reduced number of lymphocytes in the blood.
Synonyms:Absolute lymphocyte count decrease; Decreased blood lymphocyte number; Low lymphocyte number; Lymphocytopenia |
Very frequent |
Otitis media |
Inflammation or infection of the middle ear.
Synonyms:Middle ear infection |
Very frequent |
Prolonged bleeding time |
Prolongation of the time taken for a standardized skin cut of fixed depth and length to stop bleeding.
Synonyms:Increased bleeding time; Prolonged bleeding time |
Very frequent |
Recurrent respiratory infections |
An increased susceptibility to respiratory infections as manifested by a history of recurrent respiratory infections.
Synonyms:Frequent respiratory infections; Multiple respiratory infections; Recurrent respiratory infections; respiratory infections, recurrent; Susceptibility to respiratory infections |
Very frequent |
Sinusitis |
Inflammation of the paranasal sinuses owing to a viral, bacterial, or fungal infection, allergy, or an autoimmune reaction.
Synonyms:Sinus inflammation |
Very frequent |
Spontaneous hematomas |
Spontaneous development of hematomas (hematoma) or bruises without significant trauma.
|
Very frequent |
Thrombocytopenia |
A reduction in the number of circulating thrombocytes.
Synonyms:Low platelet count |
Very frequent |