Total 47 clinical symptoms reported for Walker-Warburg congenital muscular dystrophy  Very Frequent (26)Occasional (11)Frequent (10)

Abnormal cerebellar vermis morphology	An anomaly of the vermis of cerebellum.   Synonyms:Abnormality of the cerebellar vermis	Very frequent
Abnormal cortical gyration	An abnormality of the gyri (i.e., the ridges) of the cerebral cortex of the brain.   Synonyms:Abnormal gyration; Cerebral gyral anomalies	Very frequent
Abnormal optic nerve morphology	Abnormality of the optic nerve.   Synonyms:Abnormality of the optic nerve; optic nerve abnormalities; Optic nerve issue	Very frequent
Abnormality of neuronal migration	An abnormality resulting from an anomaly of neuronal migration, i.e., of the process by which neurons travel from their origin to their final position in the brain.   Synonyms:Abnormal neuronal migration; Heterotopias/abnormal migration; Migrational brain disorder; Neuronal migration disorder	Very frequent
Aplasia/Hypoplasia involving the skeletal musculature	Absence or underdevelopment of the musculature.   Synonyms:Absent/small skeletal muscles; Absent/underdeveloped skeletal muscles	Very frequent
Areflexia	Absence of neurologic reflexes such as the knee-jerk reaction.   Synonyms:Absent deep tendon reflexes; Absent tendon reflexes; Deep tendon reflexes absent; Loss of deep tendon reflexes; Lost deep tendon reflexes	Very frequent
Cerebellar hypoplasia	Cerebellar hypoplasia is a descriptive term implying a cerebellum with a reduced volume, but a normal shape and is stable over time.   Synonyms:Congenital cerebellar hypoplasia; Hypoplasia of cerebellum; Hypoplastic cerebellum; Small cerebellum; Underdeveloped cerebellum	Very frequent
Chorioretinal dysplasia	Abnormal development of the choroid and retina.	Very frequent
Global developmental delay	A delay in the achievement of motor or mental milestones in the domains of development of a child, including motor skills, speech and language, cognitive skills, and social and emotional skills. This term should only be used to describe children younger than five years of age.   Synonyms:Delayed cognitive development; Delayed development; Delayed developmental milestones; Delayed intellectual development; Delayed milestones; Delayed psychomotor development; Developmental delay; Developmental delay in early childhood; Developmental delay, global; Developmental retardation; GDD; Lack of psychomotor development; Motor and developmental delay; Motormental retardation; Psychomotor delay; Psychomotor development deficiency; Psychomotor development failure; Psychomotor developmental delay; Retarded development; Retarded mental development; Retarded psychomotor development	Very frequent
Hydrocephalus	Hydrocephalus is an active distension of the ventricular system of the brain resulting from inadequate passage of CSF from its point of production within the cerebral ventricles to its point of absorption into the systemic circulation.   Synonyms:Hydrocephaly; Nonsyndromal hydrocephalus; Too much cerebrospinal fluid in the brain	Very frequent
Hyporeflexia	Reduction of neurologic reflexes such as the knee-jerk reaction.   Synonyms:Decreased reflex response; Decreased reflexes	Very frequent
Hypotonia	Hypotonia is an abnormally low muscle tone (the amount of tension or resistance to movement in a muscle). Even when relaxed, muscles have a continuous and passive partial contraction which provides some resistance to passive stretching. Hypotonia thus manifests as diminished resistance to passive stretching. Hypotonia is not the same as muscle weakness, although the two conditions can co-exist.   Synonyms:Low muscle tone; Low or weak muscle tone; Muscle hypotonia; Muscular hypotonia	Very frequent
Intellectual disability	Intellectual disability, previously referred to as mental retardation, is characterized by subnormal intellectual functioning that occurs during the developmental period. It is defined by an IQ score below 70.   Synonyms:Intellectual disability; Mental deficiency; Mental retardation; Mental retardation, nonspecific; Mental-retardation; Nonprogressive intellectual disability; Nonprogressive mental retardation	Very frequent
Lissencephaly	A spectrum of malformations of cortical development caused by insufficient neuronal migration that subsumes the terms agyria, pachygyria and subcortical band heterotopia. See also neuropathological definitions for 2-, 3-, and 4-layered lissencephaly.   Synonyms:Fewer or absent grooves in brain	Very frequent
Metatarsus valgus	A condition in which the anterior part of the foot rotates outward away from the midline of the body and the heel remains straight.	Very frequent
Muscle weakness	Reduced strength of muscles.   Synonyms:Muscle weakness; Muscular weakness	Very frequent
Muscular dystrophy	The term dystrophy means abnormal growth. However, muscular dystrophy is used to describe primary myopathies with a genetic basis and a progressive course characterized by progressive skeletal muscle weakness and wasting, defects in muscle proteins, and histological features of muscle fiber degeneration (necrosis) and regeneration. If possible, it is preferred to use other HPO terms to describe the precise phenotypic abnormalities.	Very frequent
Optic atrophy	Atrophy of the optic nerve. Optic atrophy results from the death of the retinal ganglion cell axons that comprise the optic nerve and manifesting as a pale optic nerve on fundoscopy.   Synonyms:Optic nerve atrophy; Optic-nerve degeneration	Very frequent
Pachygyria	Pachygyria is a malformation of cortical development with abnormally wide gyri with sulci 1,5-3 cm apart and abnormally thick cortex measuring more than 5 mm (radiological definition). See also neuropathological definitions for 2-, 3-, and 4-layered lissencephaly.   Synonyms:Cerebral pachygyria; Fewer and broader ridges in brain; Macrogyria	Very frequent
Polymicrogyria	Polymicrogyria is a congenital malformation of the cerebral cortex characterized by abnormal cortical layering (lamination) and an excessive number of small gyri (folds).   Synonyms:More grooves in brain	Very frequent
Retinal detachment	Separation of the inner layers of the retina (neural retina) from the pigment epithelium.   Synonyms:Detached retina; Retinal detachment	Very frequent
Retinal dysplasia	The presence of developmental dysplasia of the retina.   Synonyms:Retinal dysgenesis	Very frequent
Retinal dystrophy	Retinal dystrophy is an abnormality of the retina associated with a hereditary process. Retinal dystrophies are defined by their predominantly monogenic inheritance and they are frequently associated with loss or dysfunction of photoreceptor cells as a primary or secondary event.   Synonyms:Breakdown of light-sensitive cells in back of eye	Very frequent
Skeletal muscle atrophy	The presence of skeletal muscular atrophy (which is also known as amyotrophy).   Synonyms:Amyotrophy; Amyotrophy involving the extremities; Muscle atrophy; Muscle atrophy, neurogenic; Muscle degeneration; Muscle hypotrophy; Muscle wasting; Muscular atrophy; Neurogenic muscle atrophy; Neurogenic muscle atrophy, especially in the lower limbs; Neurogenic muscular atrophy	Very frequent
Specific learning disability	Impairment of certain skills such as reading or writing, coordination, self-control, or attention that interfere with the ability to learn. The impairment is not related to a global deficiency of intelligence.	Very frequent
Ventriculomegaly	An increase in size of the ventricular system of the brain.   Synonyms:Cerebral ventricular dilatation; Dilated cerebral ventricle; Dilated cerebral ventricles; Dilated ventricles; Enlarged cerebral ventricles; Enlarged ventricles; Enlarged ventricular system; Large cerebral ventricles and cisternae; Ventricular dilatation	Very frequent