Total 37 clinical symptoms reported for Toxic epidermal necrolysis  Very Frequent (8)Occasional (26)Frequent (3)

Abnormal blistering of the skin	The presence of one or more bullae on the skin, defined as fluid-filled blisters more than 5 mm in diameter with thin walls.   Synonyms:Abnormal blistering of the skin; Blister; Blistering, generalized; Blisters; Skin bullae	Very frequent
Acantholysis	The loss of intercellular connections, such as desmosomes, resulting in loss of cohesion between keratinocytes.	Very frequent
Diarrhea	Abnormally increased frequency of loose or watery bowel movements.   Synonyms:Diarrhea; Watery stool	Very frequent
Erythema	Redness of the skin, caused by hyperemia of the capillaries in the lower layers of the skin.   Synonyms:Redness of skin or mucous membrane	Very frequent
Fatigue	A subjective feeling of tiredness characterized by a lack of energy and motivation.   Synonyms:Fatigue; Tired; Tiredness	Very frequent
Macule	A flat, distinct, discolored area of skin less than 1 cm wide that does not involve any change in the thickness or texture of the skin.   Synonyms:Flat, discolored area of skin	Very frequent
Nausea and vomiting	Nausea is a commonly encountered symptom that has been defined as an unpleasant painless subjective feeling that one will imminently vomit. Vomiting has been defined as the forceful expulsion of the contents of the stomach, duodenum, or jejunum through the oral cavity. While nausea and vomiting are often thought to exist on a temporal continuum, this is not always the case. There are situations when severe nausea may be present without emesis and less frequently, when emesis may be present without preceding nausea.   Synonyms:Nausea and vomiting	Very frequent
Weight loss	Reduction of total body weight.   Synonyms:Loss of weight	Very frequent