Total 58 clinical symptoms reported for Somatotroph adenoma  Very Frequent (27)Occasional (11)Frequent (20)

Abnormality of the endocrine system	An abnormality of the endocrine system.	Very frequent
Anterior hypopituitarism	A condition of reduced function of the anterior pituitary gland characterized by decreased secretion of one or more of the pituitary hormones growth hormone, thyroid-stimulating hormone, adrenocorticotropic hormone, prolactin, luteinizing hormone, and follicle-stimulating hormone.	Very frequent
Arthralgia	Joint pain.   Synonyms:Arthralgias; Joint pain	Very frequent
Broad foot	A foot for which the measured width is above the 95th centile for age; or, a foot that appears disproportionately wide for its length.   Synonyms:Broad feet; Broad foot; Wide foot	Very frequent
Broad forehead	Width of the forehead or distance between the frontotemporales is more than two standard deviations above the mean (objective); or apparently increased distance between the two sides of the forehead.   Synonyms:Bitemporal widening; Broad forehead; Increased bitemporal dimension; Increased bitemporal width; Increased width of the forehead; Intertemporal widening; Wide forehead	Very frequent
Coarse facial features	Absence of fine and sharp appearance of brows, nose, lips, mouth, and chin, usually because of rounded and heavy features or thickened skin with or without thickening of subcutaneous and bony tissues.   Synonyms:Coarse face; Coarse facial appearance; Coarse facial features; Coarse facies	Very frequent
Cortical diaphyseal thickening of the upper limbs	This information is currently in development.	Very frequent
Deep palmar crease	Excessively deep creases of the palm.   Synonyms:Deep palm line; Deep palmar creases	Very frequent
Deep plantar creases	The presence of unusually deep creases (ridges/wrinkles) on the skin of sole of foot.   Synonyms:Deep wrinkles in soles of feet	Very frequent
Elevated circulating growth hormone concentration	Acromegaly is a condition resulting from overproduction of growth hormone by the pituitary gland in persons with closed epiphyses, and consists chiefly in the enlargement of the distal parts of the body. The circumference of the skull increases, the nose becomes broad, the tongue becomes enlarged, the facial features become coarsened, the mandible grows excessively, and the teeth become separated. The fingers and toes grow chiefly in thickness.   Synonyms:Elevated circulating somatotropin concentration; Growth hormone excess; Somatotropin excess	Very frequent
Fatigue	A subjective feeling of tiredness characterized by a lack of energy and motivation.   Synonyms:Fatigue; Tired; Tiredness	Very frequent
Full cheeks	Increased prominence or roundness of soft tissues between zygomata and mandible.   Synonyms:Apple cheeks; Big cheeks; Full cheeks; Increased size of cheeks; Large cheeks	Very frequent
Hyperhidrosis	Abnormal excessive perspiration (sweating) despite the lack of appropriate stimuli like hot and humid weather.   Synonyms:Diaphoresis; Excessive sweating; Increased sweating; Profuse sweating; Sweating; Sweating profusely; Sweating, increased	Very frequent
Large hands	Synonyms:Disproportionately large hands; large hand; Large hands	Very frequent
Long face	Facial height (length) is more than 2 standard deviations above the mean (objective); or, an apparent increase in the height (length) of the face (subjective).   Synonyms:Elongation of face; Increased height of face; Increased length of face; Increased vertical dimension of face; Long face; Long facies; Vertical elongation of face; Vertical enlargement of face; Vertical excess of face; Vertical Facial Excess; Vertical hyperplasia of face; Vertical overgrowth of face	Very frequent
Long penis	Penile length more than 2 SD above the mean for age.   Synonyms:Enlarged penis; Long penis	Very frequent
Macrodactyly	Significant increase in the length and girth of most or all of a digit compared to its contralateral digit (if unaffected) or compared to what would be expected for age/body build. The increased girth is accompanied by an increase in the dorso-ventral dimension AND the lateral dimension of the digit.   Synonyms:Finger overgrowth; Megalodactyly	Very frequent
Macroglossia	Increased length and width of the tongue.   Synonyms:Abnormally large tongue; Hyperplasia of the tongue; Hypertrophy of the tongue; Increased size of tongue; Large tongue; Tongue hypertrophy	Very frequent
Macrotia	Median longitudinal ear length greater than two standard deviations above the mean and median ear width greater than two standard deviations above the mean (objective); or, apparent increase in length and width of the pinna (subjective).   Synonyms:Large ears; Large pinnae	Very frequent
Mandibular prognathia	Abnormal prominence of the chin related to increased length of the mandible.   Synonyms:Big lower jaw; Big mandible; Enlarged mandible; Enlargement of mandible; Hyperplasia of lower jaw; Increased projection of lower jaw; Increased projection of mandible; Increased size of lower jaw; Large lower jaw; Large mandible; Lower jaw excess; Lower jaw hyperplasia; Macromandible; Mandible prognathism; Mandibular excess; Mandibular hyperplasia; Mandibular macrognathia; Mandibular prognathism; Prognathia; Prognathism; Prominent chin; Prominent jaw; Prominent lower jaw; Prominent mandible; Relative mandibular prognathism	Very frequent
Osteoarthritis	Degeneration (wear and tear) of articular cartilage, i.e., of the joint surface. Joint degeneration may be accompanied by osteophytes (bone overgrowth), narrowing of the joint space, regions of sclerosis at the joint surface, or joint deformity.   Synonyms:Degenerative joint disease	Very frequent
Pituitary growth hormone cell adenoma	A type of pituitary adenoma that produces growth hormone.   Synonyms:Pituitary somatotropinoma	Very frequent
Tall stature	A height above that which is expected according to age and gender norms.   Synonyms:Accelerated linear growth; Increased body height; Increased linear growth; Tall stature	Very frequent
Tapered finger	The gradual reduction in girth of the finger from proximal to distal.   Synonyms:Distally tapering fingers; Tapered finger; Tapered fingertips; Tapering fingers	Very frequent
Thick lower lip vermilion	Increased thickness of the lower lip, leading to a prominent appearance of the lower lip. The height of the vermilion of the lower lip in the midline is more than 2 SD above the mean. Alternatively, an apparently increased height of the vermilion of the lower lip in the frontal view (subjective).   Synonyms:Full lower lip vermilion; Increased height of lower lip vermilion; Increased volume of lower lip; Increased volume of lower lip vermilion; Plump lower lip; Prominent lower lip; Thick vermilion border of lower lip	Very frequent
Thickened skin	Laminar thickening of skin.   Synonyms:Pachydermia; Thick skin; Thickened skin	Very frequent
Wide nose	Interalar distance more than two standard deviations above the mean for age, i.e., an apparently increased width of the nasal base and alae.   Synonyms:Broad nose; Increased breadth of nose; Increased nasal breadth; Increased nasal width; Increased width of nose; Wide nose	Very frequent