Total 12 clinical symptoms reported for Sea-blue histiocyte syndrome
| Abnormal bleeding |
An abnormal susceptibility to bleeding, often referred to as a bleeding diathesis. A bleeding diathesis may be related to vascular, platelet and coagulation defects.
Synonyms:Bleeding diathesis; Bleeding tendency; Hemorrhagic diathesis |
Very frequent |
| Blepharitis |
Inflammation of the eyelids.
Synonyms:Cellulitis of eyelids; Inflammation of eyelids |
Very frequent |
| Hepatomegaly |
Abnormally increased size of the liver.
Synonyms:Enlarged liver |
Very frequent |
| Mediastinal lymphadenopathy |
Swelling of lymph nodes within the mediastinum, the central compartment of the thoracic cavities that contains the heart and the great vessels, the esophagus, and trachea and other structures including lymph nodes.
Synonyms:Swollen lymph nodes in center of chest |
Very frequent |
| Petechiae |
Petechiae are pinpoint-sized reddish/purple spots, resembling a rash, that appear just under the skin or a mucous membrane when capillaries have ruptured and some superficial bleeding into the skin has happened. This term refers to an abnormally increased susceptibility to developing petechiae.
|
Very frequent |
| Sea-blue histiocytosis |
An abnormality of histiocytes, in which the cells take on a sea blue appearance due to abnormally increased lipid content. Histiocytes are a type of macrophage. Sea-blue histiocytes are typically large macrophages from 20 to 60 micrometers in diameter with a single eccentric nucleus whose cytoplasm if packed with sea-blue or blue-green granules when stained with Wright-Giemsa.
Synonyms:'Sea blue' histiocytes; Sea-blue histiocyte |
Very frequent |
| Splenomegaly |
Abnormal increased size of the spleen.
Synonyms:Increased spleen size |
Very frequent |
| Subcutaneous nodule |
Slightly elevated lesions on or in the skin with a diameter of over 5 mm.
Synonyms:Firm lump under the skin; Growth of abnormal tissue under the skin |
Very frequent |
| Thrombocytopenia |
A reduction in the number of circulating thrombocytes.
Synonyms:Low platelet count |
Very frequent |