Total 57 clinical symptoms reported for Restrictive dermopathy 1  Very Frequent (40)Occasional (16)Always (1)

Abnormality of the vasculature	An abnormality of the vasculature.   Synonyms:Abnormality of blood vessels; Abnormality of the vasculature; Vascular abnormalities	Very frequent
Aplasia/Hypoplasia involving the nose	Underdevelopment or absence of the nose or parts thereof.   Synonyms:Decreased nasal size; Decreased size of nose	Very frequent
Aplasia/Hypoplasia of the clavicles	Absence or underdevelopment of the clavicles (collar bones).   Synonyms:Absent/small collarbone; Absent/underdeveloped collarbone	Very frequent
Aplasia/Hypoplasia of the eccrine sweat glands	Absence or developmental hypoplasia of the eccrine sweat glands.   Synonyms:Hypoplastic-absent eccrine sweat glands	Very frequent
Arthrogryposis multiplex congenita	Multiple congenital contractures in different body areas.   Synonyms:Arthrogryposis; Arthrogryposis multiplex; Arthrogryposis, congenital; Multiple congenital contractures	Very frequent
Decreased fetal movement	An abnormal reduction in quantity or strength of fetal movements.   Synonyms:Decreased fetal activity; Decreased fetal movements; Decreased movement in utero; Dminished fetal movement; Fetal hypokinesia; Less than 10 fetal movements in 12 hours; Reduced fetal movement; Reduced fetal movements	Very frequent
Decreased skull ossification	A reduction in the magnitude or amount of ossification of the skull.   Synonyms:Decreased bone formation of skull; Deficient skull ossification; Hypoossification of skull; Ossification defect of skull; Poorly mineralized skull; Poorly ossified skull; Poorly ossified skull bones	Very frequent
Dermal atrophy	Partial or complete wasting (atrophy) of the skin.   Synonyms:Atrophic skin; Skin atrophy; Skin degeneration	Very frequent
Dermal translucency	An abnormally increased ability of the skin to permit light to pass through (translucency) such that subcutaneous structures such as veins display an increased degree of visibility.   Synonyms:Translucent skin	Very frequent
Downslanted palpebral fissures	The palpebral fissure inclination is more than two standard deviations below the mean.   Synonyms:Antimongoloid eye slant; Antimongoloid slant of palpebral fissures; Antimongoloid slanted palpebral fissures; Down slanting palpebral fissures; Down-slanted palpebral fissures; Down-slanting palpebral fissure; Down-slanting palpebral fissures; Downslanting palpebral fissure; Downslanting palpebral fissures; Downward slanted palpebral fissures; Downward slanting of the opening between the eyelids; Downward slanting palpebral fissures; Downward-slanting palpebral fissures; Palpebral fissures down-slanted	Very frequent
Entropion	An abnormal inversion (turning inward) of the eyelid (usually the lower) towards the globe. Entropion is usually acquired as a result of involutional or cicatricial processes but may occasionally be congenital.   Synonyms:Eyelid turned in	Very frequent
Generalized hyperkeratosis	Synonyms:Hyperkeratosis, generalized	Very frequent
Hyperkeratosis	Hyperkeratosis is a histopathological term defining a thickened stratum corneum and may be present in many different skin conditions, with many possible overlaps. Hyperkeratosis refers to the increased thickness of the stratum corneum, the outer layer of the skin. Hyperkeratosis is subclassified as orthokeratotic or parakeratotic. Orthokeratotic hyperkeratosis refers to the thickening of the keratin layer with preserved keratinocyte maturation, while parakeratotic hyperkeratosis shows retained nuclei as a sign of delayed maturation of keratinocytes.   Synonyms:Epidermal hyperkeratosis	Very frequent
Hypertelorism	Interpupillary distance more than 2 SD above the mean (alternatively, the appearance of an increased interpupillary distance or widely spaced eyes).   Synonyms:Excessive orbital separation; Increased distance between eye sockets; Increased distance between eyes; Increased interpupillary distance; Ocular hypertelorism; Wide-set eyes; Widely spaced eyes; Widened interpupillary distance	Very frequent
Increased anterioposterior diameter of thorax	Synonyms:Increased anterioposterior diameter of chest	Very frequent
Intrauterine growth retardation	An abnormal restriction of fetal growth with fetal weight below the tenth percentile for gestational age.   Synonyms:Fetal growth restriction; FGR; In utero growth retardation; Intrauterine growth failure; Intrauterine growth restriction; Intrauterine growth retardation, IUGR; Intrauterine retardation; IUGR; Prenatal growth deficiency; Prenatal growth failure; Prenatal growth retardation; Prenatal onset growth retardation; Prenatal-onset growth retardation; Small for gestational age infant	Very frequent
Low-set ears	Upper insertion of the ear to the scalp below an imaginary horizontal line drawn between the inner canthi of the eye and extending posteriorly to the ear.   Synonyms:Low set ears; Low-set ears; Low-set pinnae; Lowset ears; Melotia	Very frequent
Micrognathia	Developmental hypoplasia of the mandible.   Synonyms:Decreased size of lower jaw; Decreased size of mandible; Hypoplasia of lower jaw; Hypoplasia of mandible; Hypoplastic mandible; Hypoplastic mandible condyle; Hypotrophic lower jaw; Hypotrophic mandible; Little lower jaw; Little mandible; Lower jaw deficiency; Lower jaw hypoplasia; Mandibular deficiency; Mandibular hypoplasia; Mandibular micrognathia; Micrognathia of lower jaw; Micromandible; Robin mandible; Severe hypoplasia of mandible; Small jaw; Small lower jaw; Small mandible; Underdevelopment of lower jaw; Underdevelopment of mandible	Very frequent
Multiple joint contractures	This section is currently in development.	Very frequent
Narrow mouth	Distance between the commissures of the mouth more than 2 SD below the mean. Alternatively, an apparently decreased width of the oral aperture (subjective).   Synonyms:Microstomia; Narrow mouth; Small mouth; Small oral aperture	Very frequent
Osteopenia	Osteopenia is a term to define bone density that is not normal but also not as low as osteoporosis. By definition from the World Health Organization osteopenia is defined by bone densitometry as a T score -1 to -2.5.   Synonyms:Generalized osteopenia	Very frequent
Patent ductus arteriosus	In utero, the ductus arteriosus (DA) serves to divert ventricular output away from the lungs and toward the placenta by connecting the main pulmonary artery to the descending aorta. A patent ductus arteriosus (PDA) in the first 3 days of life is a physiologic shunt in healthy term and preterm newborn infants, and normally is substantially closed within about 24 hours after bith and completely closed after about three weeks. Failure of physiologcal closure is referred to a persistent or patent ductus arteriosus (PDA). Depending on the degree of left-to-right shunting, PDA can have clinical consequences.   Synonyms:Ductus arteriosus; Patent ductus Botalli; PDA; Persistent arterial duct; Persistent ductus arteriosus	Very frequent
Premature birth	The birth of a baby of less than 37 weeks of gestational age.   Synonyms:Premature birth; Premature delivery; Premature delivery of affected infants; Preterm birth; Preterm delivery; Shortened gestation time	Very frequent
Premature delivery because of cervical insufficiency or membrane fragility	This section is currently in development.	Very frequent
Pulmonary hypoplasia	Synonyms:Hypoplastic lung; Hypoplastic lungs; Lung hypoplasia; Poorly developed lungs; Small lung; Underdeveloped lung	Very frequent
Scaling skin	Refers to the loss of the outer layer of the epidermis in large, scale-like flakes.   Synonyms:Desquamation; flaking skin; peeling skin; Scaling skin; Scaly skin	Very frequent
Short palpebral fissure	Distance between the medial and lateral canthi is more than 2 SD below the mean for age (objective); or, apparently reduced length of the palpebral fissures.   Synonyms:Decreased height of palpebral fissure; Short opening between the eyelids; Short palpebral fissures	Very frequent
Short umbilical cord	Decreased length of the umbilical cord.   Synonyms:Short umbilical cord	Very frequent
Skin erosion	A discontinuity of the skin exhibiting incomplete loss of the epidermis, a lesion that is moist, circumscribed, and usually depressed.	Very frequent
Small placenta	Reduced size of the placenta.   Synonyms:Small placenta	Very frequent
Sparse eyebrow	Decreased density/number of eyebrow hairs.   Synonyms:Hypotrichosis of eyebrow; Sparse eyebrow; Sparse eyebrows	Very frequent
Sparse hair	Reduced density of hairs.   Synonyms:Decreased hair growth; Decreased hair growth on body; Hypotrichosis; Marked hypotrichosis; Sparse hair; Sparse hair since birth	Very frequent
Sparse or absent eyelashes	Synonyms:Sparse or absent eyelashes	Very frequent
Structural foot deformity	A foot deformity resulting due to an abnormality affecting the bones of the foot (as well as muscle and soft tissue). In contrast if only the muscle and soft tissue are affected the term positional foot deformity applies.	Very frequent
Submucous cleft hard palate	Hard-palate submucous clefts are characterized by bony defects in the midline of the bony palate that are covered by the mucous membrane of the roof of the mouth. It may be possible to detect a submucous cleft hard palate upon palpation as a notch in the bony palate.   Synonyms:Partial thickness cleft hard palate	Very frequent
Telecanthus	Distance between the inner canthi more than two standard deviations above the mean (objective); or, apparently increased distance between the inner canthi.   Synonyms:Corners of eye widely separated; Dystopia canthorum; Increased distance between medial canthi; Increased intercanthal distance	Very frequent
Temporomandibular joint ankylosis	Bony fusion of the mandibular condyle to the base of the skull, resulting in limitation of jaw opening.   Synonyms:Ankylosis of temporomandibular joint; Freezing of jaw joint; Freezing of the temporomandibular joint; Jaw ankylosis; Rigidity of the temporomandibular joint; Temporomandibular joint fusion	Very frequent
Thin clavicles	Abnormally reduced diameter (cross section) of the clavicles.   Synonyms:Thin collarbone	Very frequent
Thin ribs	Ribs with a reduced diameter.   Synonyms:Slender ribs; Thin ribs	Very frequent
Widely patent fontanelles and sutures	An abnormally increased width of the cranial fontanelles and sutures.   Synonyms:Widely patent fontanels and sutures	Very frequent