Total 42 clinical symptoms reported for Renpenning syndrome  Very Frequent (5)Occasional (19)Frequent (18)

Cachexia	Severe weight loss, wasting of muscle, loss of appetite, and general debility related to a chronic disease.   Synonyms:Wasting syndrome	Very frequent
Intellectual disability	Intellectual disability, previously referred to as mental retardation, is characterized by subnormal intellectual functioning that occurs during the developmental period. It is defined by an IQ score below 70.   Synonyms:Intellectual disability; Mental deficiency; Mental retardation; Mental retardation, nonspecific; Mental-retardation; Nonprogressive intellectual disability; Nonprogressive mental retardation	Very frequent
Microcephaly	Head circumference below 2 standard deviations below the mean for age and sex.   Synonyms:Abnormally small cranium; Abnormally small skull; Decreased circumference of cranium; Decreased size of cranium; Decreased size of skull; Reduced head circumference; small cranium; Small head circumference	Very frequent
Severe short stature	A severe degree of short stature, more than -4 SD from the mean corrected for age and sex.   Synonyms:Dwarfism; Proportionate dwarfism; Severe short stature; Short stature, extreme; Short stature, severe	Very frequent
Skeletal muscle atrophy	The presence of skeletal muscular atrophy (which is also known as amyotrophy).   Synonyms:Amyotrophy; Amyotrophy involving the extremities; Muscle atrophy; Muscle atrophy, neurogenic; Muscle degeneration; Muscle hypotrophy; Muscle wasting; Muscular atrophy; Neurogenic muscle atrophy; Neurogenic muscle atrophy, especially in the lower limbs; Neurogenic muscular atrophy	Very frequent