Total 14 clinical symptoms reported for Renal coloboma syndrome  Very Frequent (2)Occasional (6)Frequent (6)

Optic nerve dysplasia	The presence of developmental dysplasia of the optic nerve.	Very frequent
Renal insufficiency	A reduction in the level of performance of the kidneys in areas of function comprising the concentration of urine, removal of wastes, the maintenance of electrolyte balance, homeostasis of blood pressure, and calcium metabolism.   Synonyms:Renal failure; Renal failure in adulthood	Very frequent