Total 41 clinical symptoms reported for Pseudoxanthoma elasticum  Very Frequent (10)Occasional (28)Frequent (3)

Abnormal cerebral vascular morphology	An anomaly of the cerebral blood vessels.   Synonyms:Abnormality of the cerebral blood vessels; Abnormality of the cerebral vasculature	Very frequent
Abnormality of cardiovascular system morphology	Any structural anomaly of the heart and great vessels.   Synonyms:Cardiovascular malformations	Very frequent
Abnormality of the skin	An abnormality of the skin.   Synonyms:Abnormality of the skin; Dermatopathy; Dermopathy	Very frequent
Angioid streaks of the fundus	Irregular lines in the deep retina that are typically configured in a radiating fashion and emanate from the optic disc. Angioid streaks are crack-like dehiscences in abnormally thickened and calcified Bruch's membrane, resulting in atrophy of the overlying retinal pigment epithelium. They may be associated with a number of endocrine, metabolic, and connective tissue abnormalities but are frequently idiopathic.   Synonyms:Angioid streaks; Angioid streaks of the retina; Angioid streaks, retina; Knapp streaks; Laquer cracks of the retina	Very frequent
Arterial stenosis	Narrowing or constriction of the inner surface (lumen) of an artery.   Synonyms:Narrowing of an artery	Very frequent
Excessive wrinkled skin	Synonyms:Excessive wrinkled skin	Very frequent
Lack of skin elasticity	This information is currently in development.	Very frequent
Retinal hemorrhage	Hemorrhage occurring within the retina.   Synonyms:Retinal bleeding; Retinal hemorrhages	Very frequent
Retinopathy	Any noninflammatory disease of the retina. This nonspecific term is retained here because of its wide use in the literature, but if possible new annotations should indicate the precise type of retinal abnormality.   Synonyms:Noninflammatory retina disease	Very frequent
Skin rash	A red eruption of the skin.   Synonyms:Skin rash	Very frequent