Total 100 clinical symptoms reported for Proteus syndrome
Abnormal form of the vertebral bodies |
Abnormal morphology of vertebral body.
Synonyms:Abnormally shaped vertebrae |
Very frequent |
Abnormal subcutaneous fat tissue distribution |
Synonyms:Abnormal fat tissue distribution below the skin |
Very frequent |
Abnormality of finger |
An anomaly of a finger.
Synonyms:Abnormalities of the fingers; Abnormality of finger |
Very frequent |
Abnormality of skin pigmentation |
An abnormality of the pigmentation of the skin.
Synonyms:Abnormal pigmentation; Abnormal skin color; Abnormal skin pigmentation; Abnormality of pigmentation; Abnormality of skin pigmentation; Pigmentary changes; Pigmentary skin changes; Pigmentation anomaly |
Very frequent |
Arteriovenous malformation |
An anomalous configuration of blood vessels that shunts arterial blood directly into veins without passing through the capillaries.
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Very frequent |
Asymmetric growth |
A growth pattern that displays an abnormal difference between the left and the right side.
Synonyms:Uneven or disproportionate growth of one body part compared to another |
Very frequent |
Asymmetry of the thorax |
Lack of symmetry between the left and right halves of the thorax.
Synonyms:Asymmetric chest |
Very frequent |
Cachexia |
Severe weight loss, wasting of muscle, loss of appetite, and general debility related to a chronic disease.
Synonyms:Wasting syndrome |
Very frequent |
Capillary hemangioma |
The presence of a capillary hemangioma, which are hemangiomas with small endothelial spaces.
Synonyms:Capillary hemangioma; Strawberry birthmark |
Very frequent |
Decreased muscle mass |
Synonyms:Decreased muscle mass |
Very frequent |
Disproportionate tall stature |
A tall and slim body build with increased arm span to height ratio (>1.05) and a reduced upper-to-lower segment ratio (<0.85), i.e., unusually long arms and legs. The extremities as well as the hands and feet are unusually slim.
Synonyms:Dolichostenomelia; Marfanoid body habitus; Marfanoid habitus; Reduced upper-lower segment ratio |
Very frequent |
Epidermal nevus |
Epidermal naevi are due to an overgrowth of the epidermis and may be present at birth (50%) or develop during childhood.
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Very frequent |
Irregular hyperpigmentation |
This information is currently in development.
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Very frequent |
Kyphosis |
Exaggerated anterior convexity of the thoracic vertebral column.
Synonyms:Gibbus deformity; Hunched back; Hyperkyphosis; Round back |
Very frequent |
Lipoma |
Benign neoplasia derived from lipoblasts or lipocytes of white or brown fat. May be angiomatous or hibernomatous.
Synonyms:Fatty lump; Noncancerous fatty lump |
Very frequent |
Lower limb asymmetry |
A difference in length or diameter between the left and right leg.
Synonyms:Left and right leg differ in length or width |
Very frequent |
Lymphangioma |
Lymphangiomas are rare congenital malformations consisting of focal proliferations of well-differentiated lymphatic tissue in multi cystic or sponge like structures. Lymphangioma is usually asymptomatic due to its soft consistency but compression of adjacent structures can be seen due to the mass effect of a large tumor.
|
Very frequent |
Macrodactyly |
Significant increase in the length and girth of most or all of a digit compared to its contralateral digit (if unaffected) or compared to what would be expected for age/body build. The increased girth is accompanied by an increase in the dorso-ventral dimension AND the lateral dimension of the digit.
Synonyms:Finger overgrowth; Megalodactyly |
Very frequent |
Melanocytic nevus |
A oval and round, colored (usually medium-to dark brown, reddish brown, or flesh colored) lesion. Typically, a melanocytic nevus is less than 6 mm in diameter, but may be much smaller or larger.
Synonyms:Beauty mark; Melanocytic naevus; Melanocytic nevi; Nevocellular nevi; Pigmented naevi; Pigmented nevi |
Very frequent |
Scoliosis |
The presence of an abnormal lateral curvature of the spine.
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Very frequent |
Skeletal dysplasia |
A general term describing features characterized by abnormal development of bones and connective tissues.
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Very frequent |
Subcutaneous nodule |
Slightly elevated lesions on or in the skin with a diameter of over 5 mm.
Synonyms:Firm lump under the skin; Growth of abnormal tissue under the skin |
Very frequent |
Thickened skin |
Laminar thickening of skin.
Synonyms:Pachydermia; Thick skin; Thickened skin |
Very frequent |
Upper limb asymmetry |
Difference in length or size between the right and left arm.
Synonyms:Unequal size of arms |
Very frequent |
Vascular skin abnormality |
Synonyms:Skin vascular malformation |
Very frequent |