Total 16 clinical symptoms reported for Polyglandular autoimmune syndrome, type 1
| Abnormal cerebral vascular morphology |
An anomaly of the cerebral blood vessels.
Synonyms:Abnormality of the cerebral blood vessels; Abnormality of the cerebral vasculature |
Very frequent |
| Abnormal fingernail morphology |
An abnormality of the fingernails.
Synonyms:Abnormal fingernails; Abnormality of the fingernails |
Very frequent |
| Adrenal hyperplasia |
Enlargement of the adrenal gland.
Synonyms:Enlarged adrenal glands |
Very frequent |
| Autoimmunity |
The occurrence of an immune reaction against the organism's own cells or tissues.
Synonyms:Autoimmune condition; Autoimmune disease; Autoimmune disorder; Autoimmunity |
Very frequent |
| Chronic mucocutaneous candidiasis |
Recurrent or persistent superficial Candida infections of the skin, mucous membranes, and nails.
Synonyms:Chronic candidiasis of mucosa, skin and nails; Mucocutaneous candidiasis |
Very frequent |
| Decreased circulating aldosterone concentration |
Abnormally reduced levels of aldosterone.
Synonyms:Decreased aldosterone; Decreased aldosterone production; Decreased serum aldosterone; Hypoaldosteronism; Low blood aldosterone level; Mineralocorticoid insufficiency |
Very frequent |
| Hypoparathyroidism |
A condition caused by a deficiency of parathyroid hormone characterized by hypocalcemia and hyperphosphatemia.
Synonyms:Decreased parathyroid hormone secretion; Low parathyroid hormone |
Very frequent |
| Increased circulating cortisol level |
Overproduction of the hormone of cortisol by the adrenal cortex, resulting in a characteristic combination of clinical symptoms termed Cushing syndrome, with truncal obesity, a round, full face, striae atrophicae and acne, muscle weakness, and other features.
Synonyms:Cushing syndrome; Hypercortisolism; Increased circulating cortisol level; Increased cortisol production |
Very frequent |
| Opacification of the corneal stroma |
Reduced transparency of the stroma of cornea.
Synonyms:Cloudy cornea; Corneal stromal opacity |
Very frequent |
| Photophobia |
Excessive sensitivity to light with the sensation of discomfort or pain in the eyes due to exposure to bright light.
Synonyms:Extreme sensitivity of the eyes to light; Light hypersensitivity; Photodysphoria |
Very frequent |
| Primary adrenal insufficiency |
Insufficient production of steroid hormones (primarily cortisol) by the adrenal glands as a result of a primary defect in the glands themselves.
Synonyms:Adrenocortical insufficiency; Primary adrenocortical failure |
Very frequent |
| Visual impairment |
Visual impairment (or vision impairment) is vision loss (of a person) to such a degree as to qualify as an additional support need through a significant limitation of visual capability resulting from either disease, trauma, or congenital or degenerative conditions that cannot be corrected by conventional means, such as refractive correction, medication, or surgery.
Synonyms:Impaired vision; Loss of eyesight; Poor vision; Visual impairment |
Very frequent |