Total 16 clinical symptoms reported for Polyglandular autoimmune syndrome, type 1 
Abnormal cerebral vascular morphology An anomaly of the cerebral blood vessels.
 
Synonyms:Abnormality of the cerebral blood vessels; Abnormality of the cerebral vasculature
Very frequent
Abnormal fingernail morphology An abnormality of the fingernails.
 
Synonyms:Abnormal fingernails; Abnormality of the fingernails
Very frequent
Adrenal hyperplasia Enlargement of the adrenal gland.
 
Synonyms:Enlarged adrenal glands
Very frequent
Autoimmunity The occurrence of an immune reaction against the organism's own cells or tissues.
 
Synonyms:Autoimmune condition; Autoimmune disease; Autoimmune disorder; Autoimmunity
Very frequent
Chronic mucocutaneous candidiasis Recurrent or persistent superficial Candida infections of the skin, mucous membranes, and nails.
 
Synonyms:Chronic candidiasis of mucosa, skin and nails; Mucocutaneous candidiasis
Very frequent
Decreased circulating aldosterone concentration Abnormally reduced levels of aldosterone.
 
Synonyms:Decreased aldosterone; Decreased aldosterone production; Decreased serum aldosterone; Hypoaldosteronism; Low blood aldosterone level; Mineralocorticoid insufficiency
Very frequent
Hypoparathyroidism A condition caused by a deficiency of parathyroid hormone characterized by hypocalcemia and hyperphosphatemia.
 
Synonyms:Decreased parathyroid hormone secretion; Low parathyroid hormone
Very frequent
Increased circulating cortisol level Overproduction of the hormone of cortisol by the adrenal cortex, resulting in a characteristic combination of clinical symptoms termed Cushing syndrome, with truncal obesity, a round, full face, striae atrophicae and acne, muscle weakness, and other features.
 
Synonyms:Cushing syndrome; Hypercortisolism; Increased circulating cortisol level; Increased cortisol production
Very frequent
Opacification of the corneal stroma Reduced transparency of the stroma of cornea.
 
Synonyms:Cloudy cornea; Corneal stromal opacity
Very frequent
Photophobia Excessive sensitivity to light with the sensation of discomfort or pain in the eyes due to exposure to bright light.
 
Synonyms:Extreme sensitivity of the eyes to light; Light hypersensitivity; Photodysphoria
Very frequent
Primary adrenal insufficiency Insufficient production of steroid hormones (primarily cortisol) by the adrenal glands as a result of a primary defect in the glands themselves.
 
Synonyms:Adrenocortical insufficiency; Primary adrenocortical failure
Very frequent
Visual impairment Visual impairment (or vision impairment) is vision loss (of a person) to such a degree as to qualify as an additional support need through a significant limitation of visual capability resulting from either disease, trauma, or congenital or degenerative conditions that cannot be corrected by conventional means, such as refractive correction, medication, or surgery.
 
Synonyms:Impaired vision; Loss of eyesight; Poor vision; Visual impairment
Very frequent