Total 28 clinical symptoms reported for Polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy  Very Frequent (17)Occasional (3)Frequent (8)

Abnormal adipose tissue morphology	An abnormality of adipose tissue, which is loose connective tissue composed of adipocytes.   Synonyms:Abnormality of adipose tissue; Abnormality of fat tissue; Abnormality of fatty tissue	Very frequent
Abnormality of epiphysis morphology	An anomaly of epiphysis, which is the expanded articular end of a long bone that developes from a secondary ossification center, and which during the period of growth is either entirely cartilaginous or is separated from the shaft by a cartilaginous disk.   Synonyms:Abnormal shape of end part of bone; Abnormality of the epiphyses; Anomaly of the epiphyses; Epiphyseal abnormality	Very frequent
Arthralgia	Joint pain.   Synonyms:Arthralgias; Joint pain	Very frequent
Behavioral abnormality	An abnormality of mental functioning including various affective, behavioural, cognitive and perceptual abnormalities.   Synonyms:Behavioral abnormality; Behavioral changes; Behavioral disorders; Behavioral disturbances; Behavioral problems; Behavioral/psychiatric abnormalities; Behavioural/Psychiatric abnormality; Psychiatric disorders; Psychiatric disturbances	Very frequent
Bone cyst	A fluid filled cavity that develops with a bone.   Synonyms:Bone cyst; Bone cysts	Very frequent
Bone pain	An unpleasant sensation characterized by physical discomfort (such as pricking, throbbing, or aching) localized to bone.   Synonyms:Bone pain	Very frequent
Cerebral cortical atrophy	Atrophy of the cortex of the cerebrum.   Synonyms:Cerebral cortex atrophy; Cortical atrophy; Decrease in size of the outer layer of the brain due to loss of brain cells	Very frequent
Developmental regression	Loss of developmental skills, as manifested by loss of developmental milestones.   Synonyms:Loss of developmental milestones; Mental deterioration in childhood; Neurodevelopmental regression; Psychomotor regression; Psychomotor regression beginning in infancy; Psychomotor regression in infants; Psychomotor regression, progressive	Very frequent
Disinhibition	A lack of restraint manifested in several ways, including disregard for social conventions, impulsivity, and poor risk assessment.   Synonyms:Disinhibition	Very frequent
Frontal lobe dementia	This information is currently in development.	Very frequent
Irritability	A proneness to anger, i.e., a condition of being easily bothered or annoyed.   Synonyms:Irritability; Irritable	Very frequent
Limitation of joint mobility	A reduction in the freedom of movement of one or more joints.   Synonyms:Decreased joint mobility; Decreased mobility of joints; Limitation of joint mobility; Limited joint mobility; Limited joint motion	Very frequent
Memory impairment	An impairment of memory as manifested by a reduced ability to remember things such as dates and names, and increased forgetfulness.   Synonyms:Forgetfulness; Memory impairment; Memory loss; Memory problems; Poor memory	Very frequent
Personality changes	An abnormal shift in patterns of thinking, acting, or feeling.   Synonyms:Personality change; Personality changes	Very frequent
Reduced bone mineral density	A reduction of bone mineral density, that is, of the amount of matter per cubic centimeter of bones.   Synonyms:Decreased bone mineral density; Decreased bone mineral density Z score; Low solidness and mass of the bones	Very frequent
Skeletal dysplasia	A general term describing features characterized by abnormal development of bones and connective tissues.	Very frequent
Ventriculomegaly	An increase in size of the ventricular system of the brain.   Synonyms:Cerebral ventricular dilatation; Dilated cerebral ventricle; Dilated cerebral ventricles; Dilated ventricles; Enlarged cerebral ventricles; Enlarged ventricles; Enlarged ventricular system; Large cerebral ventricles and cisternae; Ventricular dilatation	Very frequent