Total 22 clinical symptoms reported for Pfeiffer syndrome  Very Frequent (3)Occasional (11)Frequent (8)

Broad thumb	Increased thumb width without increased dorso-ventral dimension.   Synonyms:Broad phalanges of the thumb; Broad thumb; Broad thumbs; Wide/broad thumb; Wide/broad thumb phalanges	Very frequent
Hypoplasia of the zygomatic bone	Underdevelopment of the zygomatic bone. That is, a reduction in size of the zygomatic bone, including the zygomatic process of the temporal bone of the skull, which forms part of the zygomatic arch.   Synonyms:Cheekbone underdevelopment; Decreased size of cheekbone; Decreased size of zygomatic bone; Hypoplasia of cheekbone; Underdevelopment of cheekbone; Underdevelopment of zygomatic bone	Very frequent
Ptosis	The upper eyelid margin is positioned 3 mm or more lower than usual and covers the superior portion of the iris (objective); or, the upper lid margin obscures at least part of the pupil (subjective).   Synonyms:Blepharoptosis; Drooping upper eyelid; Eyelid ptosis	Very frequent