Total 27 clinical symptoms reported for Pachyonychia congenita
| Hyperplastic callus formation |
Increased growth of callus, the bony and cartilaginous material that forms a connecting bridge across a bone fracture during fracture healing.
|
Very frequent |
| Lower limb pain |
An unpleasant sensation characterized by physical discomfort (such as pricking, throbbing, or aching) localized to the leg.
Synonyms:Leg pain; Lower limb pain |
Very frequent |
| Nail dystrophy |
Onychodystrophy (nail dystrophy) refers to nail changes apart from changes of the color (nail dyschromia) and involves partial or complete disruption of the various keratinous layers of the nail plate.
Synonyms:Dystrophic nails; Onychodystrophy; Poor nail formation |
Very frequent |
| Onychogryposis of toenails |
Thickened toenails.
Synonyms:Overgrowth and curving of toenails |
Very frequent |
| Palmoplantar blistering |
A type of blistering that affects the skin of the palms of the hands and the soles of the feet.
|
Very frequent |
| Palmoplantar keratoderma |
Abnormal thickening of the skin of the palms of the hands and the soles of the feet.
Synonyms:Palmar and plantar keratoderma; Thickening of palms and soles |
Very frequent |