Total 27 clinical symptoms reported for Oto-Palato-Digital syndrome  Very Frequent (14)Occasional (3)Frequent (10)

Anodontia	The absence of all teeth from the normal series by a failure to develop.   Synonyms:Anodontia vera; Complete agenesis of all teeth; Complete dental agenesis; Failure of development of all teeth	Very frequent
Cleft palate	Cleft palate is a developmental defect of the palate resulting from a failure of fusion of the palatine processes and manifesting as a separation of the roof of the mouth (soft and hard palate).   Synonyms:Cleft hard and soft palate; Cleft of hard and soft palate; Cleft of palate; Cleft palate; Cleft roof of mouth; Palatoschisis; Uranostaphyloschisis	Very frequent
Depressed nasal bridge	Posterior positioning of the nasal root in relation to the overall facial profile for age.   Synonyms:Depressed bridge of nose; Depressed nasal bridge; Depressed nasal root; Flat bridge of nose; Flat nasal bridge; Flat nasal root; Flat, nasal bridge; Flattened nasal bridge; Low nasal bridge; Low nasal root; Retruded bridge of nose; Retruded nasal bridge	Very frequent
Downslanted palpebral fissures	The palpebral fissure inclination is more than two standard deviations below the mean.   Synonyms:Antimongoloid eye slant; Antimongoloid slant of palpebral fissures; Antimongoloid slanted palpebral fissures; Down slanting palpebral fissures; Down-slanted palpebral fissures; Down-slanting palpebral fissure; Down-slanting palpebral fissures; Downslanting palpebral fissure; Downslanting palpebral fissures; Downward slanted palpebral fissures; Downward slanting of the opening between the eyelids; Downward slanting palpebral fissures; Downward-slanting palpebral fissures; Palpebral fissures down-slanted	Very frequent
Hearing impairment	A decreased magnitude of the sensory perception of sound.   Synonyms:Deafness; Hearing defect; Hearing impairment; Hypacusis	Very frequent
Hypertelorism	Interpupillary distance more than 2 SD above the mean (alternatively, the appearance of an increased interpupillary distance or widely spaced eyes).   Synonyms:Excessive orbital separation; Increased distance between eye sockets; Increased distance between eyes; Increased interpupillary distance; Ocular hypertelorism; Wide-set eyes; Widely spaced eyes; Widened interpupillary distance	Very frequent
Intellectual disability, mild	Mild intellectual disability is defined as an intelligence quotient (IQ) in the range of 50-69.   Synonyms:Intellectual disability, mild; Mental retardation, borderline-mild; Mild and nonprogressive mental retardation; Mild mental retardation	Very frequent
Limitation of joint mobility	A reduction in the freedom of movement of one or more joints.   Synonyms:Decreased joint mobility; Decreased mobility of joints; Limitation of joint mobility; Limited joint mobility; Limited joint motion	Very frequent
Oligodontia	The absence of six or more teeth from the normal series by a failure to develop.   Synonyms:Failure of development of more than six teeth; Partial anodontia	Very frequent
Prominent supraorbital ridges	Greater than average forward and/or lateral protrusion of the supraorbital portion of the frontal bones.   Synonyms:Prominent brow; Prominent supraorbital margins; Prominent supraorbital ridge; Protruding supraorbital ridge; Supraorbital hyperostosis	Very frequent
Sandal gap	A widely spaced gap between the first toe (the great toe) and the second toe.   Synonyms:Gap between 1st and 2nd toes; Gap between first and second toe; Increased space between first and second toes; Sandal gap between first and second toes; Space between great toe and second toe; Wide space between 1st, 2nd toes; Wide space between first and second toes; Wide-spaced big toe; Widely spaced 1st-2nd toes; Widely spaced first and second toes; Widened gap 1st-2nd toes; Widened gap first and second toe	Very frequent
Short hallux	Underdevelopment (hypoplasia) of the big toe.   Synonyms:Hypoplastic big toes; Hypoplastic hallux; Short big toe; Short halluces; Small hallux	Very frequent
Skeletal dysplasia	A general term describing features characterized by abnormal development of bones and connective tissues.	Very frequent
Wide nasal bridge	Increased breadth of the nasal bridge (and with it, the nasal root).   Synonyms:Broad nasal bridge; Broad nasal root; Broadened nasal bridge; Increased breadth of bridge of nose; Increased breadth of nasal bridge; Increased width of bridge of nose; Increased width of nasal bridge; Nasal bridge broad; Nasal bridge, wide; Wide bridge of nose; Wide nasal bridge; Widened nasal bridge	Very frequent