Total 15 clinical symptoms reported for Neuromyelitis optica spectrum disorder  Very Frequent (10)Occasional (4)Frequent (1)

Autoimmune antibody positivity	The presence of an antibody in the blood circulation that is directed against the organism's own cells or tissues.	Very frequent
Functional abnormality of the bladder	Dysfunction of the urinary bladder.   Synonyms:Poor bladder function	Very frequent
Myelitis	Inflammation of the spinal cord.   Synonyms:Inflammation of spinal cord	Very frequent
Neuronal loss in central nervous system	Synonyms:Loss of brain cells; Neuronal loss; Neuronal loss in CNS	Very frequent
Ocular pain	An unpleasant sensation characterized by physical discomfort (such as pricking, throbbing, or aching) localized to the eye.   Synonyms:Eye pain	Very frequent
Optic neuritis	Inflammation of the optic nerve.	Very frequent
Paraplegia	Severe or complete weakness of both lower extremities with sparing of the upper extremities.   Synonyms:Leg paralysis	Very frequent
Peripheral demyelination	A loss of myelin from the internode regions along myelinated nerve fibers of the peripheral nervous system.   Synonyms:Demyelination	Very frequent
Somatic sensory dysfunction	An abnormality of the primary sensation that is mediated by peripheral nerves (pain, temperature, touch, vibration, joint position). The word hypoesthesia (or hypesthesia) refers to a reduction in cutaneous sensation to a specific type of testing.   Synonyms:Sensory impairment	Very frequent
Visual loss	Loss of visual acuity (implying that vision was better at a certain time point in life). Otherwise the term reduced visual acuity should be used (or a subclass of that).   Synonyms:Loss of vision; Vision loss; Visual loss	Very frequent