Total 15 clinical symptoms reported for Neonatal ichthyosis-sclerosing cholangitis syndrome  Very Frequent (10)Occasional (5)

Cholestasis	Impairment of bile flow due to obstruction in bile ducts.   Synonyms:Slowed or blocked flow of bile from liver	Very frequent
Hepatomegaly	Abnormally increased size of the liver.   Synonyms:Enlarged liver	Very frequent
Ichthyosis	An abnormality of the skin characterized the presence of excessive amounts of dry surface scales on the skin resulting from an abnormality of keratinization.   Synonyms:Ichthyosiform abnormality of the skin; Ichthyotic skin	Very frequent
Jaundice	Yellow pigmentation of the skin due to bilirubin, which in turn is the result of increased bilirubin concentration in the bloodstream.   Synonyms:Icterus; Jaundice; Yellow skin; Yellowing of the skin	Very frequent
Scarring alopecia of scalp	Synonyms:Cicatricial alopecia	Very frequent
Sparse body hair	Sparseness of the body hair.   Synonyms:Limited body hair; Little body hair; Sparse body hair; Sparse to absent body hair	Very frequent
Sparse eyebrow	Decreased density/number of eyebrow hairs.   Synonyms:Hypotrichosis of eyebrow; Sparse eyebrow; Sparse eyebrows	Very frequent
Sparse eyelashes	Decreased density/number of eyelashes.   Synonyms:Hypotrichosis of eyelashes; Partial absence of eyelashes; Scant eyelashes; Scanty eyelashes; Sparse eyelashes; Thin eyelashes	Very frequent
Sparse scalp hair	Decreased number of hairs per unit area of skin of the scalp.   Synonyms:Decreased number of scalp follicles; Hypotrichosis on scalp; Reduced amount of scalp hair; Reduced/lack of hair on scalp; Reduction in the number of scalp follicles; Scalp hypotrichosis; Sparse scalp hair; Thinning scalp hair	Very frequent
Splenomegaly	Abnormal increased size of the spleen.   Synonyms:Increased spleen size; Large spleen	Very frequent