Total 101 clinical symptoms reported for Mucopolysaccharidosis, MPS-III-A  Very Frequent (10)Uncommon (10)Occasional (50)Frequent (31)

Central nervous system degeneration	Synonyms:CNS degeneration	Very frequent
Chronic otitis media	Chronic otitis media refers to fluid, swelling, or infection of the middle ear that does not heal and may cause permanent damage to the ear.   Synonyms:Chronic infections of the middle ear; Otitis media, chronic	Very frequent
Coarse hair	Hair shafts are rough in texture.   Synonyms:Coarse hair; Coarse hair texture	Very frequent
Delayed speech and language development	A degree of language development that is significantly below the norm for a child of a specified age.   Synonyms:Deficiency of speech development; Delayed language development; Delayed speech; Delayed speech acquisition; Delayed speech and language development; Delayed speech development; Impaired speech and language development; Impaired speech development; Language delay; Language delayed; Language development deficit; Late-onset speech development; Poor language development; Speech and language delay; Speech and language difficulties; Speech delay	Very frequent
Generalized hirsutism	Abnormally increased hair growth over much of the entire body.   Synonyms:Excessive hairiness over body	Very frequent
Intellectual disability, progressive	The term progressive intellectual disability should be used if intelligence decreases/deteriorates over time.   Synonyms:Intellectual disability, progressive; Mental retardation, progressive; Progressive mental retardation	Very frequent
Intellectual disability, severe	Severe mental retardation is defined as an intelligence quotient (IQ) in the range of 20-34.   Synonyms:Early and severe mental retardation; Intellectual disability, severe; Mental retardation, severe; Severe mental retardation	Very frequent
Malabsorption	Impaired ability to absorb one or more nutrients from the intestine.   Synonyms:Intestinal malabsorption; Malabsorption	Very frequent
Progressive neurologic deterioration	Synonyms:Neurologic deterioration; Neurologic deterioration, progressive; Progressive mental deterioration; Progressive neurodegeneration; Worsening neurological symptoms	Very frequent
Sleep disturbance	An abnormality of sleep including such phenomena as 1) insomnia/hypersomnia, 2) non-restorative sleep, 3) sleep schedule disorder, 4) excessive daytime somnolence, 5) sleep apnea, and 6) restlessness.   Synonyms:Difficulty sleeping; Sleep disturbances; Sleep dysfunction; Trouble sleeping	Very frequent