Total 68 clinical symptoms reported for Leigh syndrome  Very Frequent (3)Uncommon (16)Occasional (30)Frequent (19)

Abnormality of movement	An abnormality of movement with a neurological basis characterized by changes in coordination and speed of voluntary movements.   Synonyms:Abnormality of movement; Movement disorder; Unusual movement	Very frequent
Increased CSF lactate	Increased concentration of lactate in the cerebrospinal fluid.   Synonyms:Hyperlactatorachia; Increased cerebrospinal fluid lactate; Increased CSF lactic acid	Very frequent
Infantile muscular hypotonia	Muscular hypotonia (abnormally low muscle tone) manifesting in infancy.   Synonyms:Decreased muscle tone in infant; Hypotonia early; Hypotonia in infancy; Hypotonia, early; Infantile hypotonia	Very frequent