Total 16 clinical symptoms reported for Leber congenital amaurosis  Very Frequent (3)Occasional (3)Frequent (10)

Abnormality of retinal pigmentation	Synonyms:Abnormal retinal pigmentation; Abnormality of retinal pigment epithelium; Abnormality of RPE; Retinal pigmentary anomaly	Very frequent
Abnormality of the optic disc	A morphological abnormality of the optic disc, i.e., of the portion of the optic nerve clinically visible on fundoscopic examination.	Very frequent
Severely reduced visual acuity	Severe reduction of the ability to see defined as visual acuity less than 6/60 (20/200 in US notation; 0.1 in decimal notation) but at least 3/60 (20/400 in US notation; 0.05 in decimal notation).   Synonyms:Marked vision impairment; Severe reduction in visual acuity; Severe vision loss; Severe visual impairment; Severe visual loss; Severely impaired vision	Very frequent