Total 27 clinical symptoms reported for Laron-type isolated somatotropin defect
| Abnormal facial shape |
An abnormal morphology (form) of the face or its components.
Synonyms:Abnormal facial shape; Abnormal morphology of the face; Distinctive facies; Dysmorphic facial features; Dysmorphic facies; Facial dysmorphism; Unusual facial appearance; Unusual facies |
Very frequent |
| Abnormality of the endocrine system |
An abnormality of the endocrine system.
|
Very frequent |
| Aplasia/Hypoplasia involving the nose |
Underdevelopment or absence of the nose or parts thereof.
Synonyms:Decreased nasal size; Decreased size of nose |
Very frequent |
| Delayed eruption of teeth |
Delayed tooth eruption, which can be defined as tooth eruption more than 2 SD beyond the mean eruption age.
Synonyms:Delayed dental development; Delayed dental eruption; Delayed eruption; Delayed eruption of teeth; Delayed teeth eruption; Delayed tooth eruption; Eruption, delayed; Late eruption of teeth; Late tooth eruption |
Very frequent |
| Delayed skeletal maturation |
A decreased rate of skeletal maturation. Delayed skeletal maturation can be diagnosed on the basis of an estimation of the bone age from radiographs of specific bones in the human body.
Synonyms:Delayed bone age; Delayed bone age before puberty; Delayed bone maturation; Delayed skeletal development; Retarded bone age; Skeletal maturation retardation |
Very frequent |
| High forehead |
An abnormally increased height of the forehead.
Synonyms:High forehead |
Very frequent |
| Hypoplastic nasal bridge |
Synonyms:Decreased size of bridge of nose; Decreased size of nasal bridge; Hypoplastic bridge of nose; Small bridge of nose; Small nasal bridge |
Very frequent |
| Microdontia |
Decreased size of the teeth, which can be defined as a mesiodistal tooth diameter (width) more than 2 SD below mean. Alternatively, an apparently decreased maximum width of tooth.
Synonyms:Decreased size of tooth; Decreased width of tooth; Small teeth; Small tooth; Tooth hypoplasia; Tooth hypotrophy; Underdeveloped tooth |
Very frequent |
| Micrognathia |
Developmental hypoplasia of the mandible.
Synonyms:Decreased size of lower jaw; Decreased size of mandible; Hypoplasia of lower jaw; Hypoplasia of mandible; Hypoplastic mandible; Hypoplastic mandible condyle; Hypotrophic lower jaw; Hypotrophic mandible; Little lower jaw; Little mandible; Lower jaw deficiency; Lower jaw hypoplasia; Mandibular deficiency; Mandibular hypoplasia; Mandibular micrognathia; Micrognathia of lower jaw; Micromandible; Robin mandible; Severe hypoplasia of mandible; Small jaw; Small lower jaw; Small mandible; Underdevelopment of lower jaw; Underdevelopment of mandible |
Very frequent |
| Severe short stature |
A severe degree of short stature, more than -4 SD from the mean corrected for age and sex.
Synonyms:Dwarfism; Proportionate dwarfism; Severe short stature; Short stature, extreme; Short stature, severe |
Very frequent |
| Tooth agenesis |
The absence of one or more teeth from the normal series by a failure to develop
Synonyms:Decreased tooth count; Dental agenesis; Failure of development of some teeth; Reduced number of teeth; Teeth, agenesis |
Very frequent |
| Truncal obesity |
Obesity located preferentially in the trunk of the body as opposed to the extremities.
Synonyms:Centripetal obesity; Truncal obesity |
Very frequent |