Total 44 clinical symptoms reported for Kufor-Rakeb syndrome 
Abnormal pyramidal sign Functional neurological abnormalities related to dysfunction of the pyramidal tract.
 
Synonyms:Corticospinal signs; Pyramidal signs; Pyramidal tract signs
Very frequent
Babinski sign Upturning of the big toe (and sometimes fanning of the other toes) in response to stimulation of the sole of the foot. If the Babinski sign is present it can indicate damage to the corticospinal tract.
 
Synonyms:Extensor plantar reflexes; Extensor plantar response; Extensor plantar responses; Positive Babinski sign
Very frequent
Dementia A loss of global cognitive ability of sufficient amount to interfere with normal social or occupational function. Dementia represents a loss of previously present cognitive abilities, generally in adults, and can affect memory, thinking, language, judgment, and behavior.
 
Synonyms:Dementia; Dementia, progressive; Progressive dementia
Very frequent
Lower limb hyperreflexia Increased intensity of the a reflex in the leg.
 
Synonyms:Brisk lower extremity reflexes; Hyperreflexia in lower limbs; Hyperreflexia in the lower limbs; Increased deep tendon reflexes in the lower limbs; Leg hyperreflexia; Overactive lower leg reflex
Very frequent
Parkinsonism Characteristic neurologic anomaly resulting from degeneration of dopamine-generating cells in the substantia nigra, a region of the midbrain, characterized clinically by shaking, rigidity, slowness of movement and difficulty with walking and gait.
 
Very frequent
Rigidity Continuous involuntary sustained muscle contraction. When an affected muscle is passively stretched, the degree of resistance remains constant regardless of the rate at which the muscle is stretched. This feature helps to distinguish rigidity from muscle spasticity.
 
Synonyms:Muscle rigidity; Rigidity
Very frequent
Slow saccadic eye movements An abnormally slow velocity of the saccadic eye movements.
 
Synonyms:Slow eye movements; Slow saccades; Slow visual tracking
Very frequent
Supranuclear gaze palsy A supranuclear gaze palsy is an inability to look in a particular direction as a result of cerebral impairment. There is a loss of the voluntary aspect of eye movements, but, as the brainstem is still intact, all the reflex conjugate eye movements are normal.
 
Synonyms:Supranuclear gaze paralysis
Very frequent
Upper limb hyperreflexia Increased intensity of the a reflex in the arm.
 
Synonyms:Hyperreflexia in upper limbs
Very frequent