Total 53 clinical symptoms reported for Hypotonia, infantile, with psychomotor retardation and characteristic facies 1  Very Frequent (9)Occasional (14)Frequent (30)

Absent speech	Complete lack of development of speech and language abilities.   Synonyms:Absent speech development; Lack of language development; Lack of speech; No speech development; No speech or language development; Nonverbal	Very frequent
Delayed speech and language development	A degree of language development that is significantly below the norm for a child of a specified age.   Synonyms:Deficiency of speech development; Delayed language development; Delayed speech; Delayed speech acquisition; Delayed speech and language development; Delayed speech development; Impaired speech and language development; Impaired speech development; Language delay; Language delayed; Language development deficit; Late-onset speech development; Poor language development; Speech and language delay; Speech and language difficulties; Speech delay	Very frequent
Esotropia	A form of strabismus with one or both eyes turned inward ('crossed') to a relatively severe degree, usually defined as 10 diopters or more.   Synonyms:Inward turning cross eyed	Very frequent
Global developmental delay	A delay in the achievement of motor or mental milestones in the domains of development of a child, including motor skills, speech and language, cognitive skills, and social and emotional skills. This term should only be used to describe children younger than five years of age.   Synonyms:Delayed cognitive development; Delayed development; Delayed developmental milestones; Delayed intellectual development; Delayed milestones; Delayed psychomotor development; Developmental delay; Developmental delay in early childhood; Developmental delay, global; Developmental retardation; Lack of psychomotor development; Motor and developmental delay; Psychomotor delay; Psychomotor development deficiency; Psychomotor development failure; Psychomotor developmental delay; Retarded development; Retarded mental development; Retarded psychomotor development	Very frequent
Infantile muscular hypotonia	Muscular hypotonia (abnormally low muscle tone) manifesting in infancy.   Synonyms:Decreased muscle tone in infant; Hypotonia early; Hypotonia in infancy; Hypotonia, early; Infantile hypotonia	Very frequent
Intellectual disability, severe	Severe mental retardation is defined as an intelligence quotient (IQ) in the range of 20-34.   Synonyms:Early and severe mental retardation; Intellectual disability, severe; Mental retardation, severe; Severe mental retardation	Very frequent
Motor delay	A type of Developmental delay characterized by a delay in acquiring motor skills.   Synonyms:Delay in motor development; Delayed early motor milestones; Delayed motor development; Delayed motor milestones; Locomotor delay; Motor developmental delay; Motor developmental milestones not achieved; Motor retardation; Retarded motor development	Very frequent
Strabismus	A misalignment of the eyes so that the visual axes deviate from bifoveal fixation. The classification of strabismus may be based on a number of features including the relative position of the eyes, whether the deviation is latent or manifest, intermittent or constant, concomitant or otherwise and according to the age of onset and the relevance of any associated refractive error.   Synonyms:Cross-eyed; Squint; Squint eyes	Very frequent
Tapered distal phalanges of finger	A reduction in diameter of the distal phalanx of finger towards the distal end.   Synonyms:Tapered distal phalanges; Tapered distal phalanges of the hand; Tapered outermost finger bone	Very frequent