Total 61 clinical symptoms reported for Hypomyelinating leukodystrophy 10
| Absent speech |
Complete lack of development of speech and language abilities.
Synonyms:Absent speech development; Lack of language development; Lack of speech; No speech development; No speech or language development; Nonverbal |
Very frequent |
| Failure to thrive |
Failure to thrive (FTT) refers to a child whose physical growth is substantially below the norm.
Synonyms:Faltering weight; FTT; Postnatal failure to thrive; Weight faltering |
Very frequent |
| Feeding difficulties |
Impaired ability to eat related to problems gathering food and getting ready to suck, chew, or swallow it.
Synonyms:Decreased oral intake; Feeding difficulties; Feeding problems; Poor feeding |
Very frequent |
| Inability to walk |
Incapability to ambulate.
Synonyms:Inability to walk; Non-ambulatory |
Very frequent |
| Intellectual disability |
The term intellectual disability or intellectual developmental disorder is used to describe significantly sub-average intellectual and adaptive functioning based on clinical assessment and as measured by individually administered, appropriately normed, standardized and validated tests of intellectual functioning and adaptive behavior, with onset during the developmental period from infancy through adolescence.
Synonyms:Intellectual disability; Mental deficiency; Mental retardation; Mental retardation, nonspecific; Mental-retardation; Nonprogressive intellectual disability; Nonprogressive mental retardation |
Very frequent |
| Progressive microcephaly |
Progressive microcephaly is diagnosed when the head circumference falls progressively behind age- and sex-dependent norms.
Synonyms:Microcephaly, postnatal, progressive; Microcephaly, progressive; Progressively abnormally small cranium; Progressively abnormally small skull |
Very frequent |
| Severe global developmental delay |
A severe delay in the achievement of motor or mental milestones in the domains of development of a child.
Synonyms:Global developmental delay, severe |
Very frequent |