Total 90 clinical symptoms reported for Hutchinson-Gilford syndrome
Absence of subcutaneous fat |
Lack of subcutaneous adipose tissue.
Synonyms:Absent fat below the skin; General absence of subcutaneous fat; Lack of fatty tissue below the skin |
Very frequent |
Conductive hearing impairment |
An abnormality of vibrational conductance of sound to the inner ear leading to impairment of sensory perception of sound.
Synonyms:Conduction deafness; Conductive deafness; Conductive hearing loss; Hearing loss, conductive |
Very frequent |
Generalized abnormality of skin |
An abnormality of the skin that is not localized to any one particular region.
Synonyms:Generalised abnormality of skin; Generalized abnormality of skin |
Very frequent |
Micrognathia |
Developmental hypoplasia of the mandible.
Synonyms:Decreased size of lower jaw; Decreased size of mandible; Hypoplasia of lower jaw; Hypoplasia of mandible; Hypoplastic mandible; Hypoplastic mandible condyle; Hypotrophic lower jaw; Hypotrophic mandible; Little lower jaw; Little mandible; Lower jaw deficiency; Lower jaw hypoplasia; Lower jaw retrusion; Mandibular deficiency; Mandibular hypoplasia; Mandibular micrognathia; Mandibular retrognathia; Mandibular retrusion; Micrognathia of lower jaw; Micromandible; Robin mandible; Severe hypoplasia of mandible; Small jaw; Small lower jaw; Small mandible; Underdevelopment of lower jaw; Underdevelopment of mandible |
Very frequent |
Narrow mouth |
Distance between the commissures of the mouth more than 2 SD below the mean. Alternatively, an apparently decreased width of the oral aperture (subjective).
Synonyms:Microstomia; Narrow mouth; Small mouth; Small oral aperture |
Very frequent |
Premature skin wrinkling |
The presence of an increased degree of wrinkling (irregular folds and indentations) of the skin as compared with age-related norms.
Synonyms:Premature skin wrinkling |
Very frequent |
Prominent superficial blood vessels |
Synonyms:Prominent superficial blood vessels; Prominent superficial vasculature |
Very frequent |
Prominent umbilicus |
Abnormally prominent umbilicus (belly button).
Synonyms:Prominent belly button; Prominent navel |
Very frequent |
Pubertal developmental failure in females |
This information is currently in development.
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Very frequent |
Severe failure to thrive |
Synonyms:Marked failure to thrive; Severe faltering weight; Severe postnatal failure to thrive; Severe weight faltering |
Very frequent |
Thin vermilion border |
Height of the vermilion of the medial part of the lip more than 2 SD below the mean, or apparently reduced height of the vermilion of the lip in the frontal view. The vermilion is the red part of the lips (and confusingly, the vermilion itself is also often referred to as being equivalent the lips).
Synonyms:Decreased volume of lip; Decreased volume of lip vermillion; Thin lips; Thin vermillion |
Very frequent |
Weight loss |
Reduction of total body weight.
Synonyms:Loss of weight |
Very frequent |