Total 16 clinical symptoms reported for Hirschsprung disease 
Abdominal pain An unpleasant sensation characterized by physical discomfort (such as pricking, throbbing, or aching) and perceived to originate in the abdomen.
 
Synonyms:Abdominal pain; Pain in stomach; Stomach pain
Very frequent
Aganglionic megacolon An abnormality resulting from a lack of intestinal ganglion cells (i.e., an aganglionic section of bowel) that results in bowel obstruction with enlargement of the colon.
 
Synonyms:Congenital megacolon; Enlarged colon lacking nerve cells; Hirschsprung megacolon; Megacolon
Very frequent
Constipation Infrequent or difficult evacuation of feces.
 
Synonyms:Constipation; Costiveness; Dyschezia
Very frequent
Functional abnormality of the gastrointestinal tract Abnormal functionality of the gastrointestinal tract.
 
Synonyms:Functional abnormality of the GI tract; GI dysfunction
Very frequent
Intestinal obstruction Blockage or impairment of the normal flow of the contents of the intestine towards the anal canal.
 
Synonyms:Bowel obstruction; Intestinal blockage; Intestinal obstruction
Very frequent
Nausea and vomiting Nausea is a commonly encountered symptom that has been defined as an unpleasant painless subjective feeling that one will imminently vomit. Vomiting has been defined as the forceful expulsion of the contents of the stomach, duodenum, or jejunum through the oral cavity. While nausea and vomiting are often thought to exist on a temporal continuum, this is not always the case. There are situations when severe nausea may be present without emesis and less frequently, when emesis may be present without preceding nausea.
 
Synonyms:Nausea and vomiting
Very frequent