Total 13 clinical symptoms reported for Hereditary factor VIII deficiency disease  Very Frequent (3)Uncommon (2)Occasional (5)Frequent (3)

Arthralgia	Joint pain.   Synonyms:Arthralgias; Joint pain	Very frequent
Bleeding with minor or no trauma	Significant bleeding or hemorrhage without significant precipitating factor.   Synonyms:Bleeding with minor or no trauma; Easy bleeding	Very frequent
Reduced factor VIII activity	Reduced activity of coagulation factor VIII. Factor VIII (fVIII) is a cofactor in the intrinsic clotting cascade that is activated to fVIIIa in the presence of minute quantities of thrombin. fVIIIa acts as a receptor, for factors IXa and X.	Very frequent