Total 15 clinical symptoms reported for Griscelli syndrome type 1  Very Frequent (12)Occasional (1)Frequent (2)

Abnormality of movement	An abnormality of movement with a neurological basis characterized by changes in coordination and speed of voluntary movements.   Synonyms:Abnormality of movement; Movement disorder; Unusual movement	Very frequent
Ataxia	Cerebellar ataxia refers to ataxia due to dysfunction of the cerebellum. This causes a variety of elementary neurological deficits including asynergy (lack of coordination between muscles, limbs and joints), dysmetria (lack of ability to judge distances that can lead to under- or overshoot in grasping movements), and dysdiadochokinesia (inability to perform rapid movements requiring antagonizing muscle groups to be switched on and off repeatedly).   Synonyms:Cerebellar ataxia	Very frequent
Diplopia	Diplopia is a condition in which a single object is perceived as two images, it is also known as double vision.   Synonyms:Double vision	Very frequent
Generalized hypotonia	Generalized muscular hypotonia (abnormally low muscle tone).   Synonyms:Generalized decreased muscle tone; Generalized muscular hypotonia; Hypotonia, generalized	Very frequent
Hypertonia	A condition in which there is increased muscle tone so that arms or legs, for example, are stiff and difficult to move.   Synonyms:Hypertonicity; Increased muscle tone	Very frequent
Iris hypopigmentation	An abnormal reduction in the amount of pigmentation of the iris.   Synonyms:Light eye color; Reduced iris pigmentation	Very frequent
Nystagmus	Rhythmic, involuntary oscillations of one or both eyes related to abnormality in fixation, conjugate gaze, or vestibular mechanisms.   Synonyms:Involuntary, rapid, rhythmic eye movements	Very frequent
Partial albinism	Absence of melanin pigment in various areas, which is found at birth and is permanent. The lesions are known as leucoderma and are often found on the face, trunk, or limbs.   Synonyms:Congenital partial albinism on face, trunk, or limbs; Congenital partial leucoderma; Partial absent skin pigmentation	Very frequent
Premature graying of hair	Development of gray hair at a younger than normal age.   Synonyms:Early graying; Premature graying; Premature graying of hair; Premature hair graying	Very frequent
Retinopathy	Any noninflammatory disease of the retina. This nonspecific term is retained here because of its wide use in the literature, but if possible new annotations should indicate the precise type of retinal abnormality.   Synonyms:Noninflammatory retina disease	Very frequent
Seizure	A seizure is an intermittent abnormality of nervous system physiology characterized by a transient occurrence of signs and/or symptoms due to abnormal excessive or synchronous neuronal activity in the brain.   Synonyms:Epileptic seizure; Seizures	Very frequent
White hair	Hypopigmented hair that appears white.   Synonyms:White hair	Very frequent