Total 15 clinical symptoms reported for Frasier syndrome  Very Frequent (6)Uncommon (1)Frequent (5)Always (3)

Decreased serum estradiol	A reduction below normal concentration of estradiol in the circulation.   Synonyms:Decreased serum estradiol	Very frequent
Focal segmental glomerulosclerosis	Segmental accumulation of scar tissue in individual (but not all) glomeruli.   Synonyms:Focal and segmental glomerular sclerosis; Focal and segmental glomerulosclerosis; focal glomerulosclerosis	Very frequent
Gonadal dysgenesis with female appearance, male	Unusual gonadal development in a person with a 46,XY male karyotype, leading to a more female sex differentiation.	Very frequent
Hypergonadotropic hypogonadism	Reduced function of the gonads (testes in males or ovaries in females) associated with excess pituitary gonadotropin secretion and resulting in delayed sexual development and growth delay.   Synonyms:Hypergonadotrophic hypogonadism; Primary hypogonadism	Very frequent
Increased circulating gonadotropin level	Overproduction of gonadotropins (FSH, LH) by the anterior pituitary gland.   Synonyms:Elevated gonadotropins; Elevated serum gonadotropins; Gonadotropin excess; Increased circulating gonadotropin level	Very frequent
Primary amenorrhea	This section is currently in development.	Very frequent