Total 24 clinical symptoms reported for Fetal akinesia deformation sequence 1 
Absent palmar crease The absence of the major creases of the palm (distal transverse crease, proximal transverse crease, or thenar crease).
 
Synonyms:Absence of the palmar creases; Absent palm lines; Aplasia of the palmar creases
Very frequent
Akinesia Inability to initiate changes in activity or movement and to perform ordinary volitional movements rapidly and easily.
 
Very frequent
Arthrogryposis multiplex congenita Multiple congenital contractures in different body areas.
 
Synonyms:Arthrogryposis; Arthrogryposis multiplex; Arthrogryposis, congenital; Multiple congenital contractures
Very frequent
Camptodactyly of finger The distal interphalangeal joint and/or the proximal interphalangeal joint of the fingers cannot be extended to 180 degrees by either active or passive extension.
 
Synonyms:Camptodactyly of hands; Camptodactyly of proximal interphalangeal joint; Contractures of the proximal interphalangeal joints of the fingers; Flexion contractures of proximal interphalangeal joints; Permanent flexion of the finger; Proximal interphalangeal finger joint contractures
Very frequent
Excessive daytime somnolence A state of abnormally strong desire for sleep during the daytime.
 
Synonyms:Excessive daytime sleepiness; More than typical sleepiness during day
Very frequent
Fetal akinesia sequence Decreased fetal activity associated with multiple joint contractures, facial anomalies and pulmonary hypoplasia. Ultrasound examination may reveal polyhydramnios, ankylosis, scalp edema, and decreased chest movements (reflecting pulmonary hypoplasia).
 
Very frequent
Hypokinesia Abnormally diminished motor activity. In contrast to paralysis, hypokinesia is not characterized by a lack of motor strength, but rather by a poverty of movement. The typical habitual movements (e.g., folding the arms, crossing the legs) are reduced in frequency.
 
Synonyms:Decreased muscle movement; Decreased spontaneous movement; Decreased spontaneous movements
Very frequent
Intrauterine growth retardation An abnormal restriction of fetal growth with fetal weight below the tenth percentile for gestational age.
 
Synonyms:In utero growth retardation; Intrauterine growth failure; Intrauterine growth restriction; Intrauterine growth retardation, IUGR; Intrauterine retardation; IUGR; Prenatal growth deficiency; Prenatal growth failure; Prenatal growth retardation; Prenatal onset growth retardation; Prenatal-onset growth retardation; Small for gestational age infant
Very frequent
Micrognathia Developmental hypoplasia of the mandible.
 
Synonyms:Decreased size of lower jaw; Decreased size of mandible; Hypoplasia of lower jaw; Hypoplasia of mandible; Hypoplastic mandible; Hypoplastic mandible condyle; Hypotrophic lower jaw; Hypotrophic mandible; Little lower jaw; Little mandible; Lower jaw deficiency; Lower jaw hypoplasia; Lower jaw retrusion; Mandibular deficiency; Mandibular hypoplasia; Mandibular micrognathia; Mandibular retrognathia; Mandibular retrusion; Micrognathia of lower jaw; Micromandible; Robin mandible; Severe hypoplasia of mandible; Small jaw; Small lower jaw; Small mandible; Underdevelopment of lower jaw; Underdevelopment of mandible
Very frequent
Multiple joint contractures This section is currently in development.
 
Very frequent
Pulmonary hypoplasia
 
Synonyms:Hypoplastic lung; Hypoplastic lungs; Lung hypoplasia; Poorly developed lungs; Small lung; Underdeveloped lung
Very frequent
Respiratory insufficiency
 
Synonyms:Respiratory impairment
Very frequent