Total 26 clinical symptoms reported for Epidermolysis bullosa simplex due to plakophilin deficiency
| Fragile skin |
Skin that splits easily with minimal injury.
Synonyms:Fragile skin; Skin fragility |
Very frequent |
| Nail dystrophy |
Onychodystrophy (nail dystrophy) refers to nail changes apart from changes of the color (nail dyschromia) and involves partial or complete disruption of the various keratinous layers of the nail plate.
Synonyms:Dystrophic nails; Onychodystrophy; Poor nail formation |
Very frequent |
| Palmoplantar keratoderma |
Abnormal thickening of the skin of the palms of the hands and the soles of the feet.
Synonyms:Palmar and plantar keratoderma; Thickening of palms and soles |
Very frequent |