Total 26 clinical symptoms reported for Creutzfeldt-Jakob disease  Very Frequent (4)Occasional (7)Frequent (15)

Akinetic mutism	Akinetic mutism is essentially characterized by a total absence of spontaneous behavior and speech occurring in the presence of preserved visual tracking.	Very frequent
Cerebral cortex with spongiform changes	This information is currently in development.	Very frequent
Dementia	A loss of global cognitive ability of sufficient amount to interfere with normal social or occupational function. Dementia represents a loss of previously present cognitive abilities, generally in adults, and can affect memory, thinking, language, judgment, and behavior.   Synonyms:Dementia; Dementia, progressive; Progressive dementia	Very frequent
Neuronal loss in central nervous system	Synonyms:Loss of brain cells; Neuronal loss; Neuronal loss in CNS	Very frequent