Total 57 clinical symptoms reported for Cowden Syndrome  Very Frequent (10)Occasional (28)Frequent (19)

Breast carcinoma	The presence of a carcinoma of the breast.   Synonyms:Breast cancer	Very frequent
Colorectal polyposis	Multiple abnormal growths that arise from the lining of the large intestine (colon or rectum) and protrude into the intestinal lumen.   Synonyms:Colorectal polyps	Very frequent
Conjunctival hamartoma	A hamartoma (disordered proliferation of mature tissues) of the conjunctiva.	Very frequent
Generalized hyperkeratosis	Synonyms:Hyperkeratosis, generalized	Very frequent
Goiter	An enlargement of the thyroid gland.   Synonyms:Enlarged thyroid gland in neck; Thyroid goiter	Very frequent
Macule	A flat, distinct, discolored area of skin less than 1 cm wide that does not involve any change in the thickness or texture of the skin.   Synonyms:Flat, discolored area of skin	Very frequent
Neoplasm of the skin	A tumor (abnormal growth of tissue) of the skin.   Synonyms:Dermatological tumors; Skin tumors; Tumor of the skin	Very frequent
Palmoplantar keratoderma	Abnormal thickening of the skin of the palms of the hands and the soles of the feet.   Synonyms:Palmar and plantar keratoderma; Thickening of palms and soles	Very frequent
Papilloma	A tumor of the skin or mucous membrane with finger-like projections.	Very frequent
Papule	A circumscribed, solid elevation of skin with no visible fluid, varying in size from a pinhead to less than 10mm in diameter at the widest point.   Synonyms:Papules	Very frequent