Total 25 clinical symptoms reported for Congenital afibrinogenemia  Very Frequent (25)

Abdominal pain	An unpleasant sensation characterized by physical discomfort (such as pricking, throbbing, or aching) and perceived to originate in the abdomen.   Synonyms:Abdominal pain; Pain in stomach; Stomach pain	Very frequent
Abnormal bleeding	An abnormal susceptibility to bleeding, often referred to as a bleeding diathesis. A bleeding diathesis may be related to vascular, platelet and coagulation defects.   Synonyms:Bleeding diathesis; Bleeding tendency; Hemorrhagic diathesis	Very frequent
Abnormal umbilical stump bleeding	Abnormal bleeding of the umbilical stump following separation of the cord at approximately 7-10 days after birth.	Very frequent
Abnormality of cardiovascular system morphology	Any structural anomaly of the heart and great vessels.   Synonyms:Cardiovascular malformations	Very frequent
Abnormality of the subungual region	A lesion located beneath a fingernail or toenail.	Very frequent
Anaphylactic shock	An acute hypersensitivity reaction due to exposure to a previously encountered antigen.   Synonyms:Anaphylaxis	Very frequent
Bruising susceptibility	An ecchymosis (bruise) refers to the skin discoloration caused by the escape of blood into the tissues from ruptured blood vessels. This term refers to an abnormally increased susceptibility to bruising. The corresponding phenotypic abnormality is generally elicited on medical history as a report of frequent ecchymoses or bruising without adequate trauma.   Synonyms:Bruisability; Bruise easily; Bruising susceptibility; Easy bruisability; Easy bruising	Very frequent
Clubbing of fingers	Terminal broadening of the fingers (distal phalanges of the fingers).   Synonyms:Clubbed fingers; Clubbing (hands); Clubbing of fingers; Finger clubbing	Very frequent
Cyanosis	Bluish discoloration of the skin and mucosa due to poor circulation or inadequate oxygenation of arterial or capillary blood.   Synonyms:Blue discoloration of the skin	Very frequent
Decreased testicular size	Reduced volume of the testicle (the male gonad).   Synonyms:Decreased testicular size; Hypoplastic testes; Small testes; Small testis; Testicular hypoplasia	Very frequent
Developmental cataract	A cataract that occurs congenitally as the result of a developmental defect, in contrast to the majority of cataracts that occur in adulthood as the result of degenerative changes of the lens.   Synonyms:Bilateral congenital cataracts; Cataract, congenital; Clouding of the lens of the eye at birth; Congenital cataract; Congenital cataracts; Congenital cataracts, bilateral	Very frequent
Gingival bleeding	Hemorrhage affecting the gingiva.   Synonyms:Bleeding gums; Gingival hemorrhage; Gingivorrhagia	Very frequent
Hemorrhagic ovarian cyst	An abdominal mass formed by bleeding into a follicular ovarian cyst or corpus luteum cyst.	Very frequent
Internal hemorrhage	The presence of hemorrhage within the body.   Synonyms:Internal bleeding	Very frequent
Left ventricular hypertrophy	Enlargement or increased size of the heart left ventricle.   Synonyms:Heart left ventricle hypertrophy; Left ventricular wall hypertrophy	Very frequent
Loss of consciousness	Synonyms:Loss of consciousness; Passing out	Very frequent
Micropenis	Abnormally small penis. At birth, the normal penis is about 3 cm (stretched length from pubic tubercle to tip of penis) with micropenis less than 2.0-2.5 cm.   Synonyms:Short penis; Small penis	Very frequent
Microphthalmia	A developmental anomaly characterized by abnormal smallness of one or both eyes.   Synonyms:Abnormally small eyeball; Abnormally small globe of eye; Microphthalmos	Very frequent
Opisthotonus	Synonyms:Opisthotonos	Very frequent
Prolonged prothrombin time	Increased time to coagulation in the prothrombin time test, which is a measure of the extrinsic pathway of coagulation. The results of the prothrombin time test are often expressed in terms of the International normalized ratio (INR), which is calculated as a ratio of the patient's prothrombin time (PT) to a control PT standardized for the potency of the thromboplastin reagent developed by the World Health Organization (WHO) using the formula: INR is equal to Patient PT divided by Control PT.   Synonyms:Increased INR; Increased international normalized ratio; Low factor II activity; Prolonged PT; Reduced factor II activity; Reduced prothrombin activity	Very frequent
Right ventricular hypertrophy	In this case the right ventricle is more muscular than normal, causing a characteristic boot-shaped (coeur-en-sabot) appearance as seen on anterior- posterior chest x-rays. Right ventricular hypertrophy is commonly associated with any form of right ventricular outflow obstruction or pulmonary hypertension, which may in turn owe its origin to left-sided disease. The echocardiographic signs are thickening of the anterior right ventricular wall and the septum. Cavity size is usually normal, or slightly enlarged. In many cases there is associated volume overload present due to tricuspid regurgitation, in the absence of this, septal motion is normal.   Synonyms:Heart right ventricle hypertrophy	Very frequent
Splenic rupture	A breach of the capsule of the spleen.   Synonyms:Ruptured spleen; Splenic rupture	Very frequent
Subcutaneous hemorrhage	This term refers to an abnormally increased susceptibility to bruising (purpura, petechiae, or ecchymoses).   Synonyms:Bleeding below the skin	Very frequent
Tachycardia	A rapid heartrate that exceeds the range of the normal resting heartrate for age.   Synonyms:Fast heart rate; Heart racing; Racing heart	Very frequent
Volvulus	Abnormal twisting of a portion of intestine around itself or around a stalk of mesentery tissue.	Very frequent