Total 17 clinical symptoms reported for Combined immunodeficiency due to DOCK8 deficiency  Very Frequent (14)Occasional (3)

Asthma	Asthma is characterized by increased responsiveness of the tracheobronchial tree to multiple stimuli, leading to narrowing of the air passages with resultant dyspnea, cough, and wheezing.   Synonyms:Asthma; Bronchial asthma	Very frequent
Atopic dermatitis	Atopic dermatitis (AD) or atopic eczema is an itchy, inflammatory skin condition with a predilection for the skin flexures. It is characterized by poorly defined erythema with edema, vesicles, and weeping in the acute stage and skin thickening (lichenification) in the chronic stage.   Synonyms:Atopic dermatitis, chronic; Dermatitis, Atopic	Very frequent
B lymphocytopenia	An abnormal decrease from the normal count of B cells.   Synonyms:B cell deficiency; B cell lymphopenia; Decreased B cell count; Low B cell count; Reduction in B cell number	Very frequent
Chronic otitis media	Chronic otitis media refers to fluid, swelling, or infection of the middle ear that does not heal and may cause permanent damage to the ear.   Synonyms:Chronic infections of the middle ear; Otitis media, chronic	Very frequent
Onychomycosis	A fungal infection of the toenails or fingernails that tends to cause the nails to thicken, discolor, disfigure, and split.	Very frequent
Pneumonia	Inflammation of any part of the lung parenchyma.   Synonyms:Pneumonia	Very frequent
Recurrent bacterial skin infections	Increased susceptibility to bacterial infections of the skin, as manifested by recurrent episodes of infectious dermatitis.   Synonyms:Recurrent bacterial skin infections; Recurrent cutaneous pyogenic infections; Recurrent episodes of impetigo; Recurrent episodes of infectious dermatitis; Recurrent pyogenic skin infections	Very frequent
Recurrent candida infections	An increased susceptibility to candida infections, as manifested by a history of recurrent episodes of candida infections.   Synonyms:Frequent candida infections	Very frequent
Recurrent respiratory infections	An increased susceptibility to respiratory infections as manifested by a history of recurrent respiratory infections.   Synonyms:Frequent respiratory infections; Multiple respiratory infections; Recurrent respiratory infections; respiratory infections, recurrent; Susceptibility to respiratory infections	Very frequent
Recurrent sinusitis	A recurrent form of sinusitis.   Synonyms:Sinusitis, recurrent	Very frequent
Recurrent viral infections	Increased susceptibility to viral infections, as manifested by recurrent episodes of viral infection.	Very frequent
Skin ulcer	A discontinuity of the skin exhibiting complete loss of the epidermis and often portions of the dermis and even subcutaneous fat.   Synonyms:Open skin sore	Very frequent
T lymphocytopenia	An abnormally low count of T cells.   Synonyms:Decrease in T cell count; Decrease in T cell number; Decreased numbers of circulating T cells; Low T cell count; Reduced number of T cells	Very frequent
Verrucae	Warts, benign growths on the skin or mucous membranes that cause cosmetic problems as well as pain and discomfort. Warts most often occur on the hands, feet, and genital areas.   Synonyms:Warts	Very frequent