Total 10 clinical symptoms reported for Charcot-Marie-Tooth disease axonal type 2F
| Distal lower limb amyotrophy |
Muscular atrophy of distal leg muscles.
Synonyms:Lower leg amyotrophy; Lower limb degeneration; Muscle atrophy, lower limb, distal |
Very frequent |
| Impaired pain sensation |
Reduced ability to perceive painful stimuli.
Synonyms:Decreased pain sensation; Decreased pinprick sensation; Impaired pain sensation |
Very frequent |
| Impaired temperature sensation |
A reduced ability to discriminate between different temperatures.
Synonyms:Abnormality of temperature sensation; Impaired temperature sensation; Impaired thermal sensitivity; Loss of temperature sensation |
Very frequent |
| Limb fasciculations |
Fasciculations affecting the musculature of the arms and legs.
Synonyms:Limb fasciculation |
Very frequent |
| Lower limb muscle weakness |
Weakness of the muscles of the legs.
Synonyms:Leg weakness; Lower extremity weakness; Lower limb muscle weakness; Lower limb weakness; Muscle weakness in lower limbs |
Very frequent |
| Peripheral axonal neuropathy |
An abnormality characterized by disruption of the normal functioning of peripheral axons.
Synonyms:Axonal neuropathy; Axonal peripheral neuropathy |
Very frequent |
| Reduced tendon reflexes |
Diminution of tendon reflexes, which is an invariable sign of peripheral nerve disease.
Synonyms:Absent or decreased deep tendon reflexes; Decreased deep tendon reflexes; Decreased tendon reflexes; Decreased to absent deep tendon reflexes; Decreased/absent deep tendon reflexes; Depressed tendon reflexes; Diminished deep tendon reflexes; Diminished or absent deep tendon reflexes; Diminished or absent tendon reflexes; Hypoactive to absent deep tendon reflexes; Impaired tendon reflexes; Reduced/absent deep tendon reflexes; Weak or absent deep tendon reflexes |
Very frequent |
| Steppage gait |
An abnormal gait pattern that arises from weakness of the pretibial and peroneal muscles due to a lower motor neuron lesion. Affected patients have footdrop and are unable to dorsiflex and evert the foot. The leg is lifted high on walking so that the toes clear the ground, and there may be a slapping noise when the foot strikes the ground again.
Synonyms:High stepping |
Very frequent |
| Talipes equinovarus |
Talipes equinovarus (also called clubfoot) typically has four main components: inversion and adduction of the forefoot; inversion of the heel and hindfoot; equinus (limitation of extension) of the ankle and subtalar joint; and internal rotation of the leg.
Synonyms:Club feet; Club foot; Clubbing of feet; Clubfeet; Clubfoot; Equinovarus; Foot, talipes equinovarus; Pes equinovarus; Pes equinus; Talipes varus |
Very frequent |
| Upper limb amyotrophy |
Muscular atrophy involving the muscles of the upper limbs.
Synonyms:Amyotrophy involving the upper limbs |
Very frequent |