Total 65 clinical symptoms reported for Chédiak-Higashi syndrome 
Abnormal leukocyte morphology An abnormality of leukocytes.
 
Synonyms:Abnormality of leukocytes
Very frequent
Abnormality of multiple cell lineages in the bone marrow This section is currently in development.
 
Very frequent
Hemophagocytosis Phagocytosis by macrophages of erythrocytes, leukocytes, platelets, and their precursors in bone marrow and other tissues.
 
Very frequent
Hypopigmentation of the skin A reduction of skin color related to a decrease in melanin production and deposition.
 
Synonyms:Hypopigmentation; Hypopigmented skin; Patchy lightened skin
Very frequent
Recurrent bacterial infections Increased susceptibility to bacterial infections, as manifested by recurrent episodes of bacterial infection.
 
Synonyms:Bacterial infections, recurrent; Frequent bacterial infections; Frequent pyogenic infections; Increased susceptibility to bacterial infections; Recurrent bacterial infections; Recurrent major bacterial infections; Recurrent pyogenic infections; Susceptibility to pyogenic infection
Very frequent
Recurrent infections Increased susceptibility to infections.
 
Synonyms:Frequent infections; Frequent, severe infections; Increased frequency of infection; infections, recurrent; Predisposition to infections; Recurrent infections; Susceptibility to infection
Very frequent
Vacuolated lymphocytes The presence of clear, sharply defined vacuoles in the lymphocyte cytoplasm.
 
Synonyms:Enlarged lysosomal vacuoles in lymphocytes; Vacuolated blood lymphocytes
Very frequent