Total 20 clinical symptoms reported for Autosomal recessive juvenile Parkinson disease 2
| Bradykinesia |
Bradykinesia literally means slow movement, and is used clinically to denote a slowness in the execution of movement (in contrast to hypokinesia, which is used to refer to slowness in the initiation of movement).
Synonyms:Slow movements; Slowness of movements |
Very frequent |
| Gait disturbance |
The term gait disturbance can refer to any disruption of the ability to walk.
Synonyms:Abnormal gait; Abnormal walk; Difficulty in walking; Gait abnormalities; Gait difficulties; Gait disturbances; Impaired gait; Walking disability |
Very frequent |
| Hyperreflexia |
Hyperreflexia is the presence of hyperactive stretch reflexes of the muscles.
Synonyms:Increased deep tendon reflexes; Increased reflexes |
Very frequent |
| Hypokinesia |
Abnormally diminished motor activity. In contrast to paralysis, hypokinesia is not characterized by a lack of motor strength, but rather by a poverty of movement. The typical habitual movements (e.g., folding the arms, crossing the legs) are reduced in frequency.
Synonyms:Decreased muscle movement; Decreased spontaneous movement; Decreased spontaneous movements |
Very frequent |
| Parkinsonism |
Characteristic neurologic anomaly resulting from degeneration of dopamine-generating cells in the substantia nigra, a region of the midbrain, characterized clinically by shaking, rigidity, slowness of movement and difficulty with walking and gait.
|
Very frequent |
| Pill-rolling tremor |
A type of resting tremor characterized by simultaneous rubbing movements of thumb and index fingers against each other.
Synonyms:Pill rolling |
Very frequent |
| Rigidity |
Continuous involuntary sustained muscle contraction. When an affected muscle is passively stretched, the degree of resistance remains constant regardless of the rate at which the muscle is stretched. This feature helps to distinguish rigidity from muscle spasticity.
Synonyms:Muscle rigidity; Rigidity |
Very frequent |
| Substantia nigra gliosis |
Focal proliferation of glial cells in the substantia nigra.
|
Very frequent |
| Tremor |
An unintentional, oscillating to-and-fro muscle movement about a joint axis.
Synonyms:Tremor; Tremors |
Very frequent |